Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | GLA | P06280 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | SCN4A | P35499 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | RXRA | P19793 | 1/20 | 0.44 |
| ▸ | RXRB | P28702 | 1/20 | 0.44 |
| ▸ | RXRG | P48443 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | DRD4 | P21917 | 1/20 | 0.44 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.44 |
| ▸ | AOC2 | O75106 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11124120 | 0.83 | ALDH1A1 (0.46) | ALDH1A1GLAKDM4ECYP1A2SCN4A | |
| SCHEMBL293595 | 0.82 | HTR1B (0.56) | ALDH1A1KDM4ETDP1ALOX15TSHR | |
| SCHEMBL73523 | 0.82 | TDP1 (0.53) | ALDH1A1GLAKDM4ECYP1A2SCN4A | |
| SCHEMBL9584860 | 0.82 | KDM4E (0.46) | ALDH1A1GLAKDM4ECYP1A2TDP1 | |
| SCHEMBL11129324 | 0.81 | TDP1 (0.49) | ALDH1A1GLAKDM4ECYP1A2TDP1 | |
| SCHEMBL11101036 | 0.80 | CYP2D6 (0.54) | ALDH1A1GLAKDM4ECYP1A2TDP1 | |
| SCHEMBL1592876 | 0.80 | TDP1 (0.60) | ALDH1A1GLAKDM4ECYP1A2SCN4A | |
| SCHEMBL9808080 | 0.78 | ALDH1A1 (0.62) | ALDH1A1GLAKDM4ECYP1A2TDP1 | |
| SCHEMBL11679951 | 0.78 | CYP2D6 (0.61) | ALDH1A1GLAKDM4ECYP1A2TDP1 | |
| SCHEMBL2090885 | 0.78 | ALDH1A1 (0.53) | ALDH1A1GLAKDM4ECYP1A2SCN4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 139 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8063093-B2 | Derivatives of 5-(halo)alkanoyl-6-hydroxy- benozofuran, benzothiophene, or indole; autoimmune diseases; systemic lupus erythematosis, rheumatoid arthritis, multiple sclerosis and psoriasis, transplant rejection; antiproliferative, anticarcinogenic, antidiabetic, antiinflammatory and antiulcer agents | HARVEY ANDREW J (AU) | 2011-11-22 | — | — | US | claimed |
| US-20080221194-A1 | Novel Potassium channel Blockers and Uses Thereof | HARVEY ANDREW J | 2008-09-11 | — | — | US | claimed |
| CN-101230049-A | Hydroxamic acid histone deacetylase inhibitor as well as preparation method and use thereof | UNIV CHINA PHARMA (CN) | 2008-07-30 | — | — | CN | claimed |
| WO-2006096911-A1 | NOVEL POTASSIUM CHANNEL BLOCKERS AND USES THEREOF | HARVEY ANDREW J (AU) | 2006-09-21 | — | — | WO | claimed |
| US-4379788-A | HYPOTENSIVES, ANTIARRHYTHMIA, B-BLOCKERS | DR. KARL THOMAE GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1983-04-12 | — | — | US | claimed |
| US-4252716-A | BLUE SHADES | BAYER AKTIENGESELLSCHAFT (DE) | 1981-02-24 | — | — | US | claimed |
| US-3991042-A | Basic azo dyestuffs containing a benzthiazole and a tetrahydroquinoline nucleus | BAYER AKTIENGESELLSCHAFT (DT) | 1976-11-09 | — | — | US | claimed |
| CN-112400002-B | Adhesive composition and adhesive tape | 综研化学株式会社 | 2022-10-11 | — | — | CN | disclosed |
| CN-115073661-A | Resin composition and display device using same | 三星显示有限公司 | 2022-09-20 | — | — | CN | disclosed |
| CN-111742022-B | Double-sided adhesive sheet and use thereof | 综研化学株式会社 | 2022-04-12 | — | — | CN | disclosed |
| CN-112400002-A | Adhesive composition and adhesive tape | 综研化学株式会社 | 2021-02-23 | — | — | CN | disclosed |
| CN-111742022-A | Double-sided adhesive sheet and use thereof | 综研化学株式会社 | 2020-10-02 | — | — | CN | disclosed |
| WO-2020027180-A1 | ADHESIVE AGENT COMPOSITION AND ADHESIVE TAPE | 綜研化学株式会社 | 2020-02-06 | — | — | WO | disclosed |
| US-4154945-A | Fungicidal substituted imidazoles | THE BOOTS COMPANY LIMITED (GB) | 1979-05-15 | — | — | US | disclosed |
| US-4080462-A | Fungicidal compositions containing substituted imidazoles | THE BOOTS COMPANY LIMITED (EN) | 1978-03-21 | — | — | US | disclosed |
| US-4075163-A | STABILIZATION | SANDOZ LTD. (CH) | 1978-02-21 | — | — | US | disclosed |
| US-4045416-A | PROTECTIVE COATINGS | UNION CARBIDE CORPORATION (US) | 1977-08-30 | — | — | US | disclosed |
| US-3963771-A | PROTECTIVE COATINGS | UNION CARBIDE CORPORATION (US) | 1976-06-15 | — | — | US | disclosed |
| US-3962175-A | BENZENE PHOSPHONOUS ACID COMPOUNDS, THEIR PRODUCTION AND USE AS STABILIZERS FOR ORGANIC MATERIALS | SANDOZ LTD. (CH) | 1976-06-08 | — | — | US | disclosed |
| US-3954847-A | STABILIZERS | SANDOZ LTD. (CH) | 1976-05-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080221194-A1 | Novel Potassium channel Blockers and Uses Thereof | KCNAB1, KCNB1, KCNMB1 | ALDH1A1 982/4885GLA 3422/4885KDM4E 971/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.