Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.43 |
| ▸ | PGR | P06401 | 1/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | MGAM | O43451 | 1/20 | 0.43 |
| ▸ | SI | P14410 | 1/20 | 0.43 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5365497 | 0.96 | CYP1A2 (0.53) | CYP1A2NR1I2PGRADORA3PTGS2 | |
| SCHEMBL5365566 | 0.88 | CYP1A2 (0.47) | CYP1A2NR1I2PGRADORA3PTGS2 | |
| SCHEMBL1331978 | 0.82 | CYP1A2 (0.73) | CYP1A2NR1I2PGRADORA3PTGS2 | |
| SCHEMBL50734 | 0.82 | CYP1A2 (0.73) | CYP1A2NR1I2PGRADORA3PTGS2 | |
| SCHEMBL10564122 | 0.81 | CYP1A2 (0.50) | CYP1A2NR1I2PGRADORA3PTGS2 | |
| Succinic Acid Diethyl Ester SCHEMBL21518140 | 0.80 | CYP1A2 (0.70) | CYP1A2NR1I2PGRADORA3PTGS2 | |
| SCHEMBL31150447 | 0.80 | CYP1A2 (0.70) | CYP1A2NR1I2PGRADORA3PTGS2 | |
| SCHEMBL12199120 | 0.80 | CYP1A2 (0.53) | CYP1A2NR1I2PGRADORA3PTGS2 | |
| SCHEMBL5351732 | 0.79 | TSHR (0.65) | GAAMGAMSIMGAM2L3MBTL1 | |
| SCHEMBL8570508 | 0.78 | CYP1A2 (0.73) | CYP1A2NR1I2PGRADORA3PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070238781-A1 | Compounds for the modulation of the glykolysis-enzyme-and/or of the transaminase-complex | EIGENBRODT ERICH | 2007-10-11 | — | — | US | disclosed |
| US-7223784-B2 | Compounds for the modulation of the glycolysis enzyme and/or transaminase complex | ScheBo® Biotech AG (DE) | 2007-05-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070238781-A1 | Compounds for the modulation of the glykolysis-enzyme-and/or of the transaminase-complex | PC, GOT1, PCK1 | CYP1A2 508/4885NR1I2 1392/4885PGR 3435/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.