Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7290612 | 0.82 | LMNA (0.46) | GRIN2BTAAR1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL20137513 | 0.81 | LMNA (0.49) | GRIN2BTAAR1MEN1KMT2A | |
| SCHEMBL20069595 | 0.81 | UTS2R (0.45) | GRIN2BALDH1A1KDM4EPOLBMEN1 | |
| SCHEMBL22857083 | 0.80 | GRIN2B (0.41) | GRIN2BALDH1A1KDM4EPOLBMEN1 | |
| SCHEMBL3772435 | 0.79 | USP2 (0.39) | USP2TSHRP2RX7 | |
| SCHEMBL376479 | 0.78 | MAPK1 (0.41) | GRIN2BTSHRALDH1A1KDM4ETAAR1 | |
| SCHEMBL10614529 | 0.78 | USP2 (0.41) | USP2TSHR | |
| SCHEMBL10191864 | 0.78 | ALDH1A1 (0.44) | GRIN2BUSP2TSHRALDH1A1TAAR1 | |
| SCHEMBL7105614 | 0.78 | USP2 (0.41) | USP2TSHR | |
| SCHEMBL10192225 | 0.78 | ALDH1A1 (0.44) | GRIN2BUSP2TSHRALDH1A1TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7273952-B2 | Substituted C-cyclohexylmethylamine derivatives | GRUENENTHAL GMBH (DE) | 2007-09-25 | — | — | US | disclosed |