Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 14/20 | 0.48 |
| ▸ | CA2 | P00918 | 14/20 | 0.48 |
| ▸ | CA12 | O43570 | 10/20 | 0.48 |
| ▸ | CA7 | P43166 | 10/20 | 0.48 |
| ▸ | CA13 | Q8N1Q1 | 9/20 | 0.48 |
| ▸ | CA9 | Q16790 | 7/20 | 0.42 |
| ▸ | CA4 | P22748 | 3/20 | 0.42 |
| ▸ | CA6 | P23280 | 3/20 | 0.42 |
| ▸ | CA5A | P35218 | 3/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.42 |
| ▸ | CA5B | Q9Y2D0 | 3/20 | 0.42 |
| ▸ | CA3 | P07451 | 2/20 | 0.39 |
| ▸ | SOS1 | Q07889 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | AGO2 | Q9UKV8 | 1/20 | 0.36 |
| ▸ | PTGES2 | Q9H7Z7 | 4/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1522482 | 0.83 | CA1 (0.42) | CA1CA2CA12CA7CA13 | |
| SCHEMBL2776177 | 0.78 | CA1 (0.62) | CA1CA2CA12CA7CA13 | |
| SCHEMBL31000067 | 0.78 | CA1 (0.62) | CA1CA2CA12CA7CA13 | |
| SCHEMBL677588 | 0.75 | CA1 (0.52) | CA1CA2CA12CA7CA13 | |
| SCHEMBL2776346 | 0.74 | CA2 (0.46) | CA1CA2CA12CA7CA13 | |
| SCHEMBL3782946 | 0.73 | CA1 (0.45) | CA1CA2CA12CA7CA13 | |
| SCHEMBL2937321 | 0.71 | CA1 (0.48) | CA1CA2CA12CA7CA13 | |
| SCHEMBL29674875 | 0.69 | ALDH1A1 (0.38) | CA9CA6CA5ACA14CA5B | |
| SCHEMBL5507464 | 0.69 | ALDH1A1 (0.38) | CA9CA6CA5ACA14CA5B | |
| SCHEMBL2775322 | 0.69 | PTGS1 (0.42) | CA1CA2CA12CA7CA13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7268129-B2 | Fluorinated benzothiadiazine compounds | LES LABORATOIRES SERVIER (FR) | 2007-09-11 | — | — | US | disclosed |
| US-20050165008-A1 | Fluorinated benzothiadiazine compounds | LES LABORATORIES SERVIER (FR) | 2005-07-28 | — | — | US | disclosed |
| EP-1557412-A1 | Fluorinated benzothiadiazine derivatives and their use as AMPA receptor modulators | Les Laboratoires Servier (FR) | 2005-07-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050165008-A1 | Fluorinated benzothiadiazine compounds | GRM1, GRIN1, GRIK5 | CA1 1787/4885CA2 1644/4885CA12 3098/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.