SCHEMBL1522482

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5348292	0.83	CA1 (0.48)	CA1CA2CA7CA12CA13
	SCHEMBL1522319	0.79	CA2 (0.40)	CA1CA2CA7CA12CA13
	SCHEMBL2775322	0.78	PTGS1 (0.42)	CA1CA2CA7CA12CA13
	SCHEMBL13006836	0.73	ACHE (0.44)	CA1CA2CA7CA12CA13
	SCHEMBL1522738	0.73	PKM (0.41)	CA1CA2CA12PTGS1PTGS2
	SCHEMBL21808336	0.72	CA12 (0.48)	CA1CA2CA7CA12CA13
	SCHEMBL31000067	0.72	CA1 (0.62)	CA1CA2CA7CA12CA13
	SCHEMBL2776177	0.72	CA1 (0.62)	CA1CA2CA7CA12CA13
	SCHEMBL29720164	0.71	POLB (0.46)	ALDH1A1KDM4EPOLBNPC1CYP3A4
	SCHEMBL3670713	0.71	POLB (0.46)	ALDH1A1KDM4EPOLBNPC1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.