SCHEMBL5349019

SCHEMBL5349019

Bc1c(F)c(F)c(OC)c(F)c1F

nearest known ligand 0.35

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 1/20 0.35
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5358108 0.95 HSD17B10 (0.33) HSD17B10
SCHEMBL7784272 0.85 HSD17B10 (0.32) HSD17B10
SCHEMBL3763099 0.84 HSD17B10 (0.41) HSD17B10MEN1KMT2A
SCHEMBL182607 0.81 HSD17B10 (0.40) HSD17B10MEN1KMT2A
Tromethamine SCHEMBL7028618 0.77 MEN1 (0.34) HSD17B10MEN1KMT2A
SCHEMBL1711725 0.75 HSD17B10 (0.47) HSD17B10MEN1KMT2A
SCHEMBL4951694 0.74 HSD17B10 (0.35) HSD17B10
SCHEMBL15299589 0.73
SCHEMBL5351309 0.73
SCHEMBL10019857 0.73 HSD17B10 (0.36) HSD17B10MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8383862-B2 Salt compound, cationic polymerization initiator and cationically polymerizable composition ADEKA CORPORATION (JP) 2013-02-26 US disclosed
US-20100267857-A1 SALT COMPOUND, CATIONIC POLYMERIZATION INITIATOR AND CATIONICALLY POLYMERIZABLE COMPOSITION ADEKA CORPORATION (JP) 2010-10-21 US disclosed
US-7217676-B2 Hydrophobization and silica for supported catalyst EXXON MOBIL CHEMICAL PATENTS INC. (US) 2007-05-15 US disclosed
EP-1704171-A2 HYDROPHOBIZATION AND SILICA FOR SUPPORTED CATALYST ExxonMobil Chemical Patents Inc. (US) 2006-09-27 EP disclosed
WO-2005075526-A2 HYDROPHOBIZATION AND SILICA FOR SUPPORTED CATALYST EXXONMOBIL CHEMICAL PATENTS INC. (US) 2005-08-18 WO disclosed
US-20050159299-A1 Hydrophobization and silica for supported catalyst EXXONMOBIL CHEMICAL PATENTS INC. 2005-07-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100267857-A1 SALT COMPOUND, CATIONIC POLYMERIZATION INITIATOR AND CATIONICALLY POLYMERIZABLE COMPOSITION RFC5, RER1, ARF5 HSD17B10 3559/4885MEN1 2796/4885KMT2A 3677/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.