SCHEMBL5349178

SCHEMBL5349178

[CH]1C=C(c2ccccc2)CCC1

nearest known ligand 0.43

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.36
CHRNB4 P30926 1/20 0.34
CHRNA3 P32297 1/20 0.34
SIGMAR1 Q99720 1/20 0.34
HTR2C P28335 1/20 0.33
HSD11B1 P28845 1/20 0.33
PKM P14618 1/20 0.31
TSHR P16473 1/20 0.31
GAA P10253 1/20 0.31
CFTR P13569 1/20 0.30
GOPC Q9HD26 1/20 0.30
ACMSD Q8TDX5 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5357998 0.85 ALDH1A1 (0.40) ALDH1A1CHRNB4CHRNA3SIGMAR1HTR2C
SCHEMBL8686265 0.79 CHRNB4 (0.44) ALDH1A1CHRNB4CHRNA3SIGMAR1HTR2C
SCHEMBL8686264 0.79 CHRNB4 (0.44) ALDH1A1CHRNB4CHRNA3SIGMAR1HTR2C
SCHEMBL360448 0.75 ACMSD (0.47) ALDH1A1SIGMAR1HTR2CACMSD
SCHEMBL6344544 0.71 ACMSD (0.49) ALDH1A1SIGMAR1HTR2CACMSD
SCHEMBL1006892 0.71 CHRNB4 (0.35) ALDH1A1CHRNB4CHRNA3SIGMAR1HTR2C
SCHEMBL1006893 0.71 CHRNB4 (0.35) ALDH1A1CHRNB4CHRNA3SIGMAR1HTR2C
SCHEMBL8778020 0.71
SCHEMBL9454254 0.69 ALDH1A1 (0.38) ALDH1A1PKMTSHRGAA
SCHEMBL8380044 0.68 ACMSD (0.49) CHRNB4CHRNA3SIGMAR1HTR2CACMSD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 62 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3589671-B1 MULTI-COMPONENT ADHESIVE SYSTEM ARKEMA FRANCE (FR) 2023-12-13 EP disclosed
WO-2018160535-A1 MULTI-COMPONENT ADHESIVE SYSTEM HERCULES LLC (US) 2018-09-07 WO disclosed
US-7250455-B2 Physical entrapment phase (e.g. organoclay) to physically prevent the agglomeration of the sub-micron \"use\" particles such as polytetrafluoroethylene (PTFE) latex which is dispersable in the target medium and imparts desirable properties while using lower amount of compatibilizing agents SHAMROCK TECHNOLOGIES, INC. (US) 2007-07-31 US disclosed
CN-1313586-C Fabric care compositions UNILEVER NV (NL) 2007-05-02 CN disclosed
US-7189769-B2 Imparting desirable properties to a target medium while using less compatibilizing agents by using a physical entrapment phase (e.g. organoclay) dispersible in said medium to physically prevent the agglomeration of the sub-micron particles such as polytetrafluoroethylene (PTFE) latex SHAMROCK TECHNOLOGIES, INC. (US) 2007-03-13 US disclosed
EP-1534779-A4 PHYSICAL METHODS OF DISPERSING CHARACTERISTICS USE PARTICLES AND COMPOSITIONS THEREOF SHAMROCK TECH INC (US) 2006-03-15 EP disclosed
EP-1545735-A4 METHOD FOR INCORPORATING CATIONIC MOLECULES INTO A SUBSTRATE FOR INCREASING DISPERSIBILITY OF CATIONIC MOLECULES CODY CHARLES A (US) 2005-09-28 EP disclosed
EP-1545735-A2 METHOD FOR INCORPORATING CATIONIC MOLECULES INTO A SUBSTRATE FOR INCREASING DISPERSIBILITY OF CATIONIC MOLECULES Shamrock Technologies, Inc. (US) 2005-06-29 EP disclosed
EP-1545756-A2 METHOD FOR INCORPORATING ANIONIC MOLECULES INTO A SUBSTRATE FOR INCREASING DISPERSIBILITY OF ANIONIC MOLECULES Shamrock Technologies, Inc. (US) 2005-06-29 EP disclosed
US-6911488-B2 Characteristic use particles entrapped within a physical entrapment phase that is dispersible in the target medium to physically prevent the agglomeration or self-association SHAMROCK TECHNOLOGIES, INC. (US) 2005-06-28 US disclosed
US-4664820-A Preactivated organophilic clay gellant lubricating grease thickened with preactivated organophilic clay gellant and process for preparing preactivated organophilic clay gellants NL INDUSTRIES, INC. (US) 1987-05-12 US disclosed
US-4659571-A SELF-SUPPORTING STICK WITH ACCEPTABLE PAYOUT; ANTIPERSPIRANTS; DEODORANTS NL INDUSTRIES, INC. (US) 1987-04-21 US disclosed
EP-0203681-A1 Compressed powder formulation containing organophilic clay and a process for making the formulation RHEOX INTERNATIONAL, INC. (US) 1986-12-03 EP disclosed
US-4620994-A Color plus clear coating system utilizing organo-modified clay PPG INDUSTRIES, INC. (US) 1986-11-04 US disclosed
US-4620993-A Color plus clear coating system utilizing organo-modified clay in combination with organic polymer microparticles PPG INDUSTRIES, INC. (US) 1986-11-04 US disclosed
US-4558075-A CROSSLINKABLE RESIN BINDER, SOLVENT SYSTEM, AND CLAY DISPERSED THEREIN PPG INDUSTRIES, INC. (US) 1985-12-10 US disclosed
US-4434075-A MODIFIED WITH AMMONIUM OR PHOSPHONIUM COMPOUNDS NL INDUSTRIES, INC. (US) 1984-02-28 US disclosed
US-4434076-A QUATERNARY AMMONIUM-SMECTITE COMPLEXES NL INDUSTRIES, INC. (US) 1984-02-28 US disclosed
US-4410364-A ORGANIC ANION-ORGANIC CATION-SMECTITE CLAY ORGANOPHILIC REACTION PRODUCT NL INDUSTRIES, INC. (US) 1983-10-18 US disclosed
US-4391637-A Rheological additive for non-aqueous fluid systems NL INDUSTRIES, INC. (US) 1983-07-05 US disclosed