SCHEMBL5349384

SCHEMBL5349384

[c]1c[c]cc(C2CCCCC2)c1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP11B2 P19099 1/20 0.38
KMO O15229 1/20 0.33
HTT P42858 2/20 0.32
KMT2A Q03164 2/20 0.32
TDP1 Q9NUW8 2/20 0.32
KDM4E B2RXH2 1/20 0.32
GLA P06280 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
HIF1A Q16665 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
LMNA P02545 1/20 0.32
ACMSD Q8TDX5 1/20 0.32
HSP90AA1 P07900 1/20 0.32
GAA P10253 1/20 0.32
MAPT P10636 1/20 0.32
BACE1 P56817 1/20 0.32
NOTUM Q6P988 1/20 0.32
HDAC8 Q9BY41 2/20 0.31
SLC18A3 Q16572 1/20 0.31
HDAC1 Q13547 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2254634 0.82 CYP11B2 (0.39) CYP11B2KMOHTTKMT2ATDP1
SCHEMBL28299085 0.79 HDAC8 (0.36) CYP11B2KMOHTTKMT2ATDP1
SCHEMBL676555 0.75 CYP11B2 (0.42) CYP11B2KMOHTTKMT2ATDP1
SCHEMBL5543159 0.75 CYP11B2 (0.42) CYP11B2KMOHTTKMT2ATDP1
SCHEMBL2911926 0.75 CYP11B2 (0.42) CYP11B2KMOHTTKMT2ATDP1
SCHEMBL22833 0.75 CYP11B2 (0.42) CYP11B2KMOHTTKMT2ATDP1
SCHEMBL23071376 0.75 CYP11B2 (0.47) CYP11B2KMOHTTKMT2ATDP1
SCHEMBL677487 0.75 CYP11B2 (0.47) CYP11B2KMOHTTKMT2ATDP1
SCHEMBL21454 0.75 CYP11B2 (0.47) CYP11B2KMOHTTKMT2ATDP1
SCHEMBL17133924 0.74 ESR2 (0.34) CYP11B2KMOACMSDHDAC8HDAC4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103403057-B The manufacture method of polyester and fluorine-containing di-carboxylic acid ester cpds ASAHI GLASS CO.,LTD. (JP) 2016-01-20 CN disclosed
US-8703899-B2 Method for producing polyester, and fluorine-containing dicarboxylic acid ester compound ASASHI GLASS COMPANY LIMITED (JP) 2014-04-22 US disclosed
US-20130345387-A1 METHOD FOR PRODUCING POLYESTER, AND FLUORINE-CONTAINING DICARBOXYLIC ACID ESTER COMPOUND ASAHI GLASS COMPANY, LIMITED (JP) 2013-12-26 US disclosed
US-7291692-B2 Polyarylene oxide and method of producing the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-11-06 US disclosed
US-20070148480-A1 Laminate TEIJIN LIMITED (JP) 2007-06-28 US disclosed
EP-1698460-A1 MULTILAYER BODY TEIJIN LIMITED (JP) 2006-09-06 EP disclosed
US-20060134407-A1 Adhesive sheet and layered product TEIJIN LIMITED (JP) 2006-06-22 US disclosed
EP-1589086-A1 ADHESIVE SHEET AND LAYERED PRODUCT TEIJIN LIMITED (JP) 2005-10-26 EP disclosed
US-20050096452-A1 Polyarylene oxide and method of producing the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2005-05-05 US disclosed