Sugi Predict

Sugi Predict / Compounds / SCHEMBL676555

SCHEMBL676555

SCHEMBL676555

[c]1ccc(C2CCCCCCC2)cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CYP11B2 P19099 1/20 0.42
▸ ESR2 Q92731 7/20 0.41
▸ HTT P42858 2/20 0.40
▸ LMNA P02545 1/20 0.40
▸ SLC18A3 Q16572 1/20 0.39
▸ HDAC1 Q13547 1/20 0.39
▸ HDAC8 Q9BY41 1/20 0.39
▸ HDAC6 Q9UBN7 1/20 0.39
▸ POLB P06746 1/20 0.39
▸ KMT2A Q03164 2/20 0.39
▸ TDP1 Q9NUW8 2/20 0.39
▸ NOTUM Q6P988 2/20 0.39
▸ HSP90AA1 P07900 1/20 0.39
▸ GAA P10253 1/20 0.39
▸ MAPT P10636 1/20 0.39
▸ HAO1 Q9UJM8 1/20 0.38
▸ ESR1 P03372 5/20 0.37
▸ CYP2D6 P10635 2/20 0.37
▸ CYP3A4 P08684 1/20 0.37
▸ CYP2C9 P11712 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5543159 1.00 CYP11B2 (0.42) CYP11B2ESR2HTTLMNASLC18A3
SCHEMBL22833 1.00 CYP11B2 (0.42) CYP11B2ESR2HTTLMNASLC18A3
SCHEMBL2911926 1.00 CYP11B2 (0.42) CYP11B2ESR2HTTLMNASLC18A3
SCHEMBL27452122 0.98 CYP11B2 (0.41) CYP11B2ESR2HTTLMNASLC18A3
SCHEMBL21538 0.97 ESR2 (0.42) CYP11B2ESR2HTTLMNASLC18A3
Fluoromethane SCHEMBL28164137 0.93 CYP11B2 (0.38) CYP11B2ESR2HTTLMNASLC18A3
SCHEMBL43455 0.92 ESR2 (0.47) CYP11B2ESR2SLC18A3HDAC1HDAC8
SCHEMBL29099563 0.91 CYP11B2 (0.37) CYP11B2ESR2HTTLMNASLC18A3
SCHEMBL6578876 0.89 POLB (0.46) ESR2SLC18A3POLBESR1CYP2D6
SCHEMBL22929 0.89 — —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 93 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0179015-B1 7-(ARYLOXY)-2-NAPHTHOXYALKANECARBOXYLIC ACID DERIVATIVES, PROCESSES FOR THE PREPARATION OF THESE COMPOUNDS, AS WELL AS AGENTS HAVING HERBICIDAL ACTIVITY CONTAINING THESE COMPOUNDS SCHERING AKTIENGESELLSCHAFT (DE) 1988-04-13 — — EP claimed
US-4089972-A Organotin sulfinates as insecticides and acaricides UNIROYAL, INC. (US) 1978-05-16 — — US claimed
CN-115989233-A Ligand compound, organic chromium compound and catalyst system comprising same 株式会社LG化学 2023-04-18 — — CN disclosed
US-20220396574-A1 LIGHT-EMITTING DEVICE, DISPLAY DEVICE, ELECTRONIC DEVICE, ORGANIC COMPOUND, AND LIGHTING DEVICE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2022-12-15 — — US disclosed
CN-109982995-B Preparation of amino acids and amino acid derivatives 优美科股份公司及两合公司 2022-09-30 — — CN disclosed
CN-114652735-A Compounds and methods for promoting myelination 凯斯西储大学 2022-06-24 — — CN disclosed
CN-109862963-B Synthesis and characterization of Ru alkylidene complexes 优美科股份公司及两合公司 2022-05-24 — — CN disclosed
CN-109641198-B Synthesis and characterization of metathesis catalysts 优美科股份公司及两合公司 2022-04-12 — — CN disclosed
CN-114206889-A Novel synthesis of Z-selective olefin metathesis catalysts 加利福尼亚技术学院 2022-03-18 — — CN disclosed
CN-114106057-A Synthesis and characterization of Ru alkylidene complexes 优美科股份公司及两合公司 2022-03-01 — — CN disclosed
CN-113924295-A Kinase inhibitors 英矽智能科技知识产权有限公司 2022-01-11 — — CN disclosed
US-4371646-A 2,6-Di-tertiary butyl phenyl phosphites and synthetic resin compositions having enhanced stability to heat and light ADEKA ARGUS CHEMICAL CO. LTD. (JP) 1983-02-01 — — US disclosed
US-4362830-A Hindered bis-phenol phenyl phosphites and synthetic resin compositions having enhanced stability to heat and light ADEKA ARGUS CHEMICAL CO., LTD. (JP) 1982-12-07 — — US disclosed
EP-0038876-A1 2,6-Di-tertiary butyl phenyl pentaerythritol spiro bis-phosphites enhancing the stability to heat and light of synthetic resins, stabilizer compositions comprising phenolic antioxidants and such phosphites, and synthetic resin compositions containing the same ADEKA ARGUS CHEMICAL CO., Ltd. (JP) 1981-11-04 — — EP disclosed
EP-0033395-A2 2,6-Di-tertiary butyl phenyl phosphites and synthetic resin compositions containing these phosphites ADEKA ARGUS CHEMICAL CO., Ltd. (JP) 1981-08-12 — — EP disclosed
EP-0032681-A2 Hindered bis-phenol phenyl phosphites and synthetic resin compositions having enhanced stability to heat and light ADEKA ARGUS CHEMICAL CO., Ltd. (JP) 1981-07-29 — — EP disclosed
US-4140681-A ANTICOAGULANTS MITSUBISHI CHEMICAL INDUSTRIES, LIMITED (JP) 1979-02-20 — — US disclosed
US-4131673-A INHIBITION AND SUPPRESSION OF THROMBOSIS IN MAMMALS MITSUBISHI CHEMICAL INDUSTRIES, LIMITED (JP) 1978-12-26 — — US disclosed
US-4125604-A PEPTIDES, ANTITHROMBOSIS MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JP) 1978-11-14 — — US disclosed
US-4097591-A ANTITHROMBOSIS MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JA) 1978-06-27 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220396574-A1 LIGHT-EMITTING DEVICE, DISPLAY DEVICE, ELECTRONIC DEVICE, ORGANIC COMPOUND, AND LIGHTING DEVICE CRY1, CYP1A1, ARNT CYP11B2 332/4885ESR2 85/4885HTT 1230/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.