Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 1/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 7/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 5/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5543159 | 1.00 | CYP11B2 (0.42) | CYP11B2ESR2HTTLMNASLC18A3 | |
| SCHEMBL2911926 | 1.00 | CYP11B2 (0.42) | CYP11B2ESR2HTTLMNASLC18A3 | |
| SCHEMBL676555 | 1.00 | CYP11B2 (0.42) | CYP11B2ESR2HTTLMNASLC18A3 | |
| SCHEMBL27452122 | 0.98 | CYP11B2 (0.41) | CYP11B2ESR2HTTLMNASLC18A3 | |
| SCHEMBL21538 | 0.97 | ESR2 (0.42) | CYP11B2ESR2HTTLMNASLC18A3 | |
| Fluoromethane SCHEMBL28164137 | 0.93 | CYP11B2 (0.38) | CYP11B2ESR2HTTLMNASLC18A3 | |
| SCHEMBL43455 | 0.92 | ESR2 (0.47) | CYP11B2ESR2SLC18A3HDAC1HDAC8 | |
| SCHEMBL29099563 | 0.91 | CYP11B2 (0.37) | CYP11B2ESR2HTTLMNASLC18A3 | |
| SCHEMBL6578876 | 0.89 | POLB (0.46) | ESR2SLC18A3POLBESR1CYP2D6 | |
| SCHEMBL22929 | 0.89 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 8566 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117143099-B | Evodiamine derivative, preparation method thereof and application of evodiamine derivative as PGAM1 inhibitor | 陕西中医药大学 | 2024-07-09 | — | — | CN | claimed |
| US-20240216900-A1 | SABRE CATALYSTS CONTAINING FLUORINATED CARBON CHAINS FOR DELIVERY OF METAL-FREE MRI CONTRAST AGENTS | THE U.S.A., AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2024-07-04 | — | — | US | claimed |
| CN-118255647-A | Preparation method of compound containing fluorine substituted cyclohexylphenyl group | 晶美晟光电材料（南京）有限公司 | 2024-06-28 | — | — | CN | claimed |
| WO-2024125652-A1 | BORON-CONTAINING ORGANIC COMPOUNDS AND ORGANIC ELECTROLUMINESCENT DEVICE PREPARED FROM SAME | 华为技术有限公司 | 2024-06-20 | — | — | WO | claimed |
| US-11982825-B2 | Liquid crystal optical element and method for manufacturing the same | JAPAN DISPLAY INC. (JP) | 2024-05-14 | — | — | US | claimed |
| CN-117843568-A | Aralkyl substituted-1-methylquinoline quaternary ammonium salt derivative and preparation method and application thereof | 中国药科大学 | 2024-04-09 | — | — | CN | claimed |
| CN-117263949-A | Heteroterpene derivative of natural product Oxirapentyn B and preparation method and application thereof | 中山大学 | 2023-12-22 | — | — | CN | claimed |
| US-20230375874-A1 | LIQUID CRYSTAL OPTICAL ELEMENT | JAPAN DISPLAY INC. (JP) | 2023-11-23 | — | — | US | claimed |
| US-20230375764-A1 | LIQUID CRYSTAL OPTICAL ELEMENT AND METHOD FOR MANUFACTURING THE SAME | JAPAN DISPLAY INC. (JP) | 2023-11-23 | — | — | US | claimed |
| WO-2023208725-A1 | AMORPHOUS COPOLYCARBONATE WITH PHENOLIC BUILDING BLOCKS | COVESTRO DEUTSCHLAND AG (DE) | 2023-11-02 | — | — | WO | claimed |
| US-4123465-A | SELECTIVE HYDROGENATION CATALYSTS | HOFFMANN-LA ROCHE INC. (US) | 1978-10-31 | — | — | US | claimed |
| US-4096338-A | ANTIPHLOGISTIC | NISSHIN FLOUR MILLING CO., LTD. (JA) | 1978-06-20 | — | — | US | claimed |
| US-4089972-A | Organotin sulfinates as insecticides and acaricides | UNIROYAL, INC. (US) | 1978-05-16 | — | — | US | claimed |
| US-4087543-A | Composition for disinfecting soil and combating plant diseases containing organic dicarbonates | BAYER AKTIENGESELLSCHAFT (DT) | 1978-05-02 | — | — | US | claimed |
| US-4042617-A | FROM A GLYCIDIC ACID ESTER | NISSHIN FLOUR MILLING CO., LTD. (JA) | 1977-08-16 | — | — | US | claimed |
| US-4016196-A | HEATING GLYCIDIC ESTERS | NISSHIN FLOUR MILLING CO., LTD. (JA) | 1977-04-05 | — | — | US | claimed |
| US-4016191-A | WATER INSOLUBLE; LIGHTFASTNESS | BAYER AKTIENGESELLSCHAFT (DT) | 1977-04-05 | — | — | US | claimed |
| US-4007217-A | FROM A GLYCIDATE | NISSHIN FLOUR MILLING CO., LTD. (JA) | 1977-02-08 | — | — | US | claimed |
| US-3971804-A | ACARICIDES, FUNGICIDES, INSECTICIDES | BAYER AKTIENGESELLSCHAFT (DT) | 1976-07-27 | — | — | US | claimed |
| US-3959332-A | N-(2-NITRO-4-ARYLOXYSULFONYL-PHENYL)-ARYLENEDIAMINES, DYES | SANDOZ LTD. (CH) | 1976-05-25 | — | — | US | claimed |