Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 1/20 | 0.47 |
| ▸ | DPP4 | P27487 | 1/20 | 0.42 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.42 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.42 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.42 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.42 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.41 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6809984 | 0.86 | ITGB3 (0.47) | TGM2ITGB3ITGA2BHDAC4HDAC1 | |
| SCHEMBL6809258 | 0.85 | TGM2 (0.46) | TGM2ITGB3ITGA2BHDAC4HDAC1 | |
| SCHEMBL5355999 | 0.82 | DPP4 (0.58) | DPP4DPP8DPP9DPP7HDAC1 | |
| SCHEMBL12291405 | 0.82 | TGM2 (0.45) | TGM2DPP4DPP8DPP9DPP7 | |
| Hydrochloric Acid SCHEMBL5346118 | 0.81 | DPP4 (0.57) | DPP4DPP8DPP9DPP7HDAC1 | |
| SCHEMBL5871953 | 0.79 | TGM2 (0.44) | TGM2DPP4DPP8DPP9DPP7 | |
| SCHEMBL10054478 | 0.78 | TGM2 (0.46) | TGM2DPP4DPP8DPP9DPP7 | |
| SCHEMBL10078265 | 0.78 | TGM2 (0.46) | TGM2DPP4DPP8DPP9DPP7 | |
| SCHEMBL2859559 | 0.77 | DPP4 (0.66) | TGM2DPP4DPP8DPP9DPP7 | |
| SCHEMBL2859552 | 0.77 | DPP4 (0.66) | TGM2DPP4DPP8DPP9DPP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7189728-B2 | Inhibitors of dipeptidyl peptidase IV | FERRING, BV (NL) | 2007-03-13 | — | — | US | disclosed |
| US-7125863-B2 | Inhibitors of dipeptidyl peptidase IV | FERRING BV (NL) | 2006-10-24 | — | — | US | disclosed |
| EP-1693365-A1 | Inhibitors of dipeptidyl peptidase IV | FERRING B.V. (NL) | 2006-08-23 | — | — | EP | disclosed |
| EP-1280797-B1 | INHIBITORS OF DIPEPTIDYL PEPTIDASE IV | FERRING BV (NL) | 2004-10-13 | — | — | EP | disclosed |
| US-20040082497-A1 | Inhibitors of dipeptidyl peptidase IV | FERRING BV (NL) | 2004-04-29 | — | — | US | disclosed |
| US-20030216450-A1 | Inhibitors of dipeptidyl peptidase IV | FERRING BV (NL) | 2003-11-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030216450-A1 | Inhibitors of dipeptidyl peptidase IV | DPP4, DPP7, DPP8 | TGM2 648/4885DPP4 1/4885DPP8 3/4885 |
| US-20040082497-A1 | Inhibitors of dipeptidyl peptidase IV | DPP4, DPP7, DPP3 | TGM2 1289/4885DPP4 1/4885DPP8 6/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.