Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 known ✓ | P35372 | 1/20 | 0.50 |
| ▸ | OPRD1 known ✓ | P41143 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 5/20 | 0.90 |
| ▸ | MAPT | P10636 | 4/20 | 0.90 |
| ▸ | POLB | P06746 | 3/20 | 0.90 |
| ▸ | MEN1 | O00255 | 2/20 | 0.90 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.90 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.90 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.90 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.90 |
| ▸ | TYMS | P04818 | 3/20 | 0.57 |
| ▸ | GPR55 | Q9Y2T6 | 2/20 | 0.57 |
| ▸ | ESR1 | P03372 | 2/20 | 0.57 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.57 |
| ▸ | TP53 | P04637 | 2/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phosphoric Acid SCHEMBL8407059 | 0.99 | LMNA (0.87) | LMNAMAPTPOLBMEN1KMT2A | |
| Phosphoric Acid SCHEMBL11870423 | 0.99 | LMNA (0.87) | LMNAMAPTPOLBMEN1KMT2A | |
| SCHEMBL31666744 | 0.95 | LMNA (1.00) | LMNAMAPTPOLBMEN1KMT2A | |
| SCHEMBL29365023 | 0.95 | LMNA (1.00) | LMNAMAPTPOLBMEN1KMT2A | |
| SCHEMBL404777 | 0.95 | LMNA (1.00) | LMNAMAPTPOLBMEN1KMT2A | |
| SCHEMBL29174125 | 0.93 | LMNA (0.97) | LMNAMAPTPOLBMEN1KMT2A | |
| SCHEMBL16285468 | 0.90 | LMNA (0.90) | LMNAMAPTPOLBMEN1KMT2A | |
| SCHEMBL6676502 | 0.89 | LMNA (0.74) | LMNAMAPTPOLBMEN1KMT2A | |
| Phosphoric Acid SCHEMBL11870420 | 0.88 | LMNA (0.70) | LMNAMAPTPOLBMEN1KMT2A | |
| Cyanate SCHEMBL27085295 | 0.88 | LMNA (0.87) | LMNAMAPTPOLBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0825264-B1 | Stable mixture for detecting alkaline phosphatase, with a salt of o-cresolphthalein monophosphoric acid | ROCHE DIAGNOSTICS GMBH (DE) | 2004-10-13 | — | — | EP | claimed |
| US-5948631-A | COLORIMETRIC ANALYSIS OF PHOSPHATASE | ROCHE DIAGNOSTICS GMBH (DE) | 1999-09-07 | — | — | US | claimed |
| US-3975405-A | Monophosphate salt of o-cresolphthalein | COULTER DIAGNOSTICS, INC. (US) | 1976-08-17 | — | — | US | claimed |
| EP-1709186-B1 | CHARCOAL STABILIZATION OF PHENYL PHOSPHATES | SURMODICS IVD INC (US) | 2013-04-24 | — | — | EP | disclosed |
| US-7214481-B2 | Charcoal stabilization of phenyl phosphates | BIOFX LABORATORIES, INC. (US) | 2007-05-08 | — | — | US | disclosed |
| US-20060063220-A1 | Charcoal stabilization of phenyl phosphates | BIOFX LABORATORIES, INC. (US) | 2006-03-23 | — | — | US | disclosed |
| US-7001717-B2 | Charcoal stabilization of phenyl phosphates | BIOFX LABORATORIES, INC. (US) | 2006-02-21 | — | — | US | disclosed |
| US-20050124024-A1 | Charcoal stabilization of phenyl phosphates | BIOFX LABORATORIES, INC. (US) | 2005-06-09 | — | — | US | disclosed |
| EP-0825264-B1 | Stable mixture for detecting alkaline phosphatase, with a salt of o-cresolphthalein monophosphoric acid | ROCHE DIAGNOSTICS GMBH (DE) | 2004-10-13 | — | — | EP | disclosed |
| US-5948631-A | COLORIMETRIC ANALYSIS OF PHOSPHATASE | ROCHE DIAGNOSTICS GMBH (DE) | 1999-09-07 | — | — | US | disclosed |
| US-5948631-A | COLORIMETRIC ANALYSIS OF PHOSPHATASE | ROCHE DIAGNOSTICS GMBH (DE) | 1999-09-07 | — | — | US | disclosed |
| US-5948631-A | COLORIMETRIC ANALYSIS OF PHOSPHATASE | ROCHE DIAGNOSTICS GMBH (DE) | 1999-09-07 | — | — | US | disclosed |
| EP-0825264-A1 | Stable mixture for detecting alkaline phosphatase, with a salt of o-cresolphthalein monophosphoric acid | Roche Diagnostics GmbH (DE) | 1998-02-25 | — | — | EP | disclosed |
| US-4985414-A | DETERMINATION OF PHOSPHATASE ENZYME | BOEHRINGER MANNHEIM GMBH (DE) | 1991-01-15 | — | — | US | disclosed |
| US-3975405-A | Monophosphate salt of o-cresolphthalein | COULTER DIAGNOSTICS, INC. (US) | 1976-08-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050124024-A1 | Charcoal stabilization of phenyl phosphates | PNP, ALPP, PRCP | OPRM1 4741/4885OPRD1 4474/4885LMNA 3210/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.