Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 7/20 | 0.48 |
| ▸ | MAOB | P27338 | 7/20 | 0.48 |
| ▸ | NISCH | Q9Y2I1 | 5/20 | 0.48 |
| ▸ | ADRA2A | P08913 | 8/20 | 0.44 |
| ▸ | ADRA2B | P18089 | 8/20 | 0.44 |
| ▸ | ADRA2C | P18825 | 8/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5352074 | 0.81 | ADRA2A (0.50) | MAOAMAOBNISCHADRA2AADRA2B | |
| SCHEMBL954219 | 0.79 | NISCH (0.56) | MAOAMAOBNISCHADRA2AADRA2B | |
| SCHEMBL9465771 | 0.76 | LMNA (0.37) | — | |
| SCHEMBL954884 | 0.72 | NISCH (0.49) | MAOAMAOBNISCHADRA2AADRA2B | |
| SCHEMBL6294162 | 0.71 | HTR2A (0.42) | — | |
| SCHEMBL953296 | 0.70 | NISCH (0.53) | MAOAMAOBNISCHADRA2AADRA2B | |
| SCHEMBL954708 | 0.70 | NISCH (0.45) | MAOAMAOBNISCHADRA2AADRA2B | |
| SCHEMBL5362545 | 0.70 | MTOR (0.38) | NISCHADRA2AADRA2BADRA2C | |
| Hydrochloric Acid SCHEMBL954763 | 0.69 | NISCH (0.51) | MAOAMAOBNISCHADRA2AADRA2B | |
| SCHEMBL954644 | 0.69 | NISCH (0.44) | MAOAMAOBNISCHADRA2AADRA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007135417-A1 | BENZOTRIAZEPINONE DERIVATIVES | JAMES BLACK FOUNDATION (GB) | 2007-11-29 | — | — | WO | claimed |
| WO-2007135417-A1 | BENZOTRIAZEPINONE DERIVATIVES | JAMES BLACK FOUNDATION (GB) | 2007-11-29 | — | — | WO | disclosed |