Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 1/20 | 0.38 |
| ▸ | ADK | P55263 | 1/20 | 0.38 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.37 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.37 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.35 |
| ▸ | F2RL1 | P55085 | 10/20 | 0.35 |
| ▸ | FPR2 | P25090 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5359242 | 0.80 | ADRA2A (0.49) | MTORADKNISCHADRA2AADRA2B | |
| SCHEMBL954734 | 0.78 | CHRM2 (0.45) | MTORADKNISCHADRA2AADRA2B | |
| SCHEMBL9465771 | 0.77 | LMNA (0.37) | — | |
| Hydrochloric Acid SCHEMBL29248987 | 0.75 | TXN (0.42) | MTORADKNISCHADRA2AADRA2B | |
| SCHEMBL6294162 | 0.72 | HTR2A (0.42) | TAAR1 | |
| SCHEMBL952173 | 0.72 | F2RL1 (0.45) | ADRA2AADRA2BADRA2CF2RL1 | |
| SCHEMBL5350240 | 0.70 | MAOA (0.48) | NISCHADRA2AADRA2BADRA2C | |
| SCHEMBL953334 | 0.69 | CHRM2 (0.43) | MTORADKNISCHADRA2AADRA2B | |
| SCHEMBL955915 | 0.69 | NISCH (0.47) | NISCHADRA2AADRA2BADRA2CF2RL1 | |
| SCHEMBL3258293 | 0.68 | FPR2 (0.50) | MTORADKNISCHADRA2AADRA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007135417-A1 | BENZOTRIAZEPINONE DERIVATIVES | JAMES BLACK FOUNDATION (GB) | 2007-11-29 | — | — | WO | claimed |
| WO-2007135417-A1 | BENZOTRIAZEPINONE DERIVATIVES | JAMES BLACK FOUNDATION (GB) | 2007-11-29 | — | — | WO | disclosed |