Known targets — ChEMBL curated mechanism
CHRM1CHRM2CHRM3CHRM4CHRM5SLC6A2dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.40 |
| ▸ | HTT | P42858 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 2/20 | 0.40 |
| ▸ | RECQL | P46063 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | APEX1 | P27695 | 1/20 | 0.40 |
| ▸ | MMP14 | P50281 | 2/20 | 0.35 |
| ▸ | RAD52 | P43351 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | THPO | P40225 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2025501 | 0.97 | LMNA (0.42) | LMNAHTTMEN1KMT2AKDM4E | |
| SCHEMBL2031262 | 0.90 | MAPT (0.44) | LMNAHTTMEN1KMT2AKDM4E | |
| Sulfuric Acid SCHEMBL4604131 | 0.85 | MAPT (0.45) | LMNAHTTMEN1KMT2AKDM4E | |
| Sulfuric Acid SCHEMBL5371996 | 0.84 | MAPT (0.44) | LMNAHTTMEN1KMT2AKDM4E | |
| SCHEMBL5462937 | 0.83 | LMNA (0.41) | LMNAHTTMEN1KMT2AKDM4E | |
| Sulfuric Acid SCHEMBL4604006 | 0.83 | MAPT (0.43) | LMNAHTTMEN1KMT2AKDM4E | |
| SCHEMBL4603649 | 0.80 | LMNA (0.41) | LMNAHTTMEN1KMT2AKDM4E | |
| SCHEMBL28339818 | 0.80 | LMNA (0.37) | LMNAHTTMEN1KMT2AKDM4E | |
| SCHEMBL14811317 | 0.80 | LMNA (0.56) | LMNAHTTMEN1KMT2AKDM4E | |
| Trifluoromethanesulfonic Acid SCHEMBL31169577 | 0.79 | MEN1 (0.40) | LMNAHTTMEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7179305-B2 | Process for dyeing keratin fibers with ninhydrin compounds comprising one or more fused rings | L'OREAL S.A. (FR) | 2007-02-20 | — | — | US | disclosed |