Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.45 |
| ▸ | MEN1 | O00255 | 5/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.45 |
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | HTT | P42858 | 4/20 | 0.45 |
| ▸ | THRB | P10828 | 4/20 | 0.45 |
| ▸ | RECQL | P46063 | 4/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | APEX1 | P27695 | 1/20 | 0.45 |
| ▸ | MMP14 | P50281 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.36 |
| ▸ | APP | P05067 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.31 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL5371996 | 0.98 | MAPT (0.44) | MAPTMEN1KMT2ALMNAHTT | |
| SCHEMBL2031262 | 0.95 | MAPT (0.44) | MAPTMEN1KMT2ALMNAHTT | |
| Sulfuric Acid SCHEMBL4604006 | 0.93 | MAPT (0.43) | MAPTMEN1KMT2ALMNAHTT | |
| SCHEMBL4603649 | 0.91 | LMNA (0.41) | MAPTMEN1KMT2ALMNAHTT | |
| Trifluoromethanesulfonic Acid SCHEMBL31169577 | 0.89 | MEN1 (0.40) | MAPTMEN1KMT2ALMNAHTT | |
| SCHEMBL10309089 | 0.89 | MAPT (0.49) | MAPTMEN1KMT2ALMNAHTT | |
| SCHEMBL136602 | 0.89 | MAPT (0.49) | MAPTMEN1KMT2ALMNAHTT | |
| SCHEMBL2025501 | 0.88 | LMNA (0.42) | MAPTMEN1KMT2ALMNAHTT | |
| Hydrochloric Acid SCHEMBL4604209 | 0.87 | MAPT (0.47) | MAPTMEN1KMT2ALMNAHTT | |
| Iodide SCHEMBL1865228 | 0.87 | MAPT (0.47) | MAPTMEN1KMT2ALMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1699427-B1 | AGENT AND METHOD FOR OXIDATIVELY DYING KERATIN FIBERS | WELLA AG (DE) | 2008-02-27 | — | — | EP | claimed |
| US-7244278-B2 | Agent and method for oxidative coloring of keratin fibers | WELLA AG (DE) | 2007-07-17 | — | — | US | claimed |
| US-20070067927-A1 | Agent and method for oxidative coloring of keratin fibers | HFC PRESTIGE INTERNATIONAL HOLDING SWITZERLAND S.A.R.L (CH) | 2007-03-29 | — | — | US | claimed |
| EP-1194633-B1 | AGENT FOR COLORING FIBERS AND METHOD FOR TEMPORARILY COLORING FIBERS | WELLA AG (DE) | 2008-04-30 | — | — | EP | disclosed |
| EP-1699427-B1 | AGENT AND METHOD FOR OXIDATIVELY DYING KERATIN FIBERS | WELLA AG (DE) | 2008-02-27 | — | — | EP | disclosed |
| EP-1341503-B1 | AGENT AND METHOD FOR DYEING KERATIN FIBRES | WELLA AG (DE) | 2008-02-13 | — | — | EP | disclosed |
| US-7244278-B2 | Agent and method for oxidative coloring of keratin fibers | WELLA AG (DE) | 2007-07-17 | — | — | US | disclosed |
| US-20070067927-A1 | Agent and method for oxidative coloring of keratin fibers | HFC PRESTIGE INTERNATIONAL HOLDING SWITZERLAND S.A.R.L (CH) | 2007-03-29 | — | — | US | disclosed |
| US-6835212-B2 | Compound with a nucleophilic reaction center, aryl alcohol or benzyl alcohol derivatives and an oxidizing enzyme | WELLA AKTIENGESELLSCHAFT (DE) | 2004-12-28 | — | — | US | disclosed |
| EP-1194118-B1 | AGENT FOR COLORING FIBERS | WELLA AG (DE) | 2004-09-15 | — | — | EP | disclosed |
| US-6740128-B2 | BLEND CONTAINING ENAMINE AND ALKALINE MIXTURE OF ALDEHYDE AND PRIMARY AMINE | WELLA AKTIENGESELLSCHAFT (DE) | 2004-05-25 | — | — | US | disclosed |
| US-6669739-B2 | Agent for coloring fibers and method for temporarily coloring fibers | WELLA AKTIENGESELLSCHAFT (DE) | 2003-12-30 | — | — | US | disclosed |
| US-20030101520-A1 | Agent for coloring fibers | WELLA INTERNATIONAL OPERATIONS SWITZERLAND SARL (CH) | 2003-06-05 | — | — | US | disclosed |
| US-20030041391-A1 | Agent and method for dyeing keratin fibres | Wella GmbH (DE) | 2003-03-06 | — | — | US | disclosed |
| US-20020172651-A1 | Agent for coloring fibers and method for temporarily coloring fibers | WELLA INTERNATIONAL OPERATIONS SWITZERLAND SARL (CH) | 2002-11-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030101520-A1 | Agent for coloring fibers | COL1A1, ENO1, H1-5 | MAPT 960/4885MEN1 996/4885KMT2A 1390/4885 |
| US-20070067927-A1 | Agent and method for oxidative coloring of keratin fibers | KRT18, KIT, AOC1 | MAPT 1792/4885MEN1 3495/4885KMT2A 751/4885 |
| US-20020172651-A1 | Agent for coloring fibers and method for temporarily coloring fibers | ENO1, H1-5, H1-2 | MAPT 1635/4885MEN1 1144/4885KMT2A 943/4885 |
| US-20030041391-A1 | Agent and method for dyeing keratin fibres | KRT18, AKR7A2, ADH5 | MAPT 844/4885MEN1 4837/4885KMT2A 651/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.