Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB11 | O95342 | 1/20 | 0.69 |
| ▸ | LMNA | P02545 | 1/20 | 0.69 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.69 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.69 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.69 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.69 |
| ▸ | DRD2 | P14416 | 1/20 | 0.69 |
| ▸ | HPGD | P15428 | 1/20 | 0.69 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.69 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.69 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.69 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.69 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.69 |
| ▸ | HTR2A | P28223 | 1/20 | 0.69 |
| ▸ | HTR2C | P28335 | 1/20 | 0.69 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.69 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.69 |
| ▸ | HRH1 | P35367 | 1/20 | 0.69 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.69 |
| ▸ | DRD3 | P35462 | 1/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tepa SCHEMBL11572 | 0.83 | ABCB11 (0.38) | ABCB11LMNACHRM2CYP3A4ADRA2A | |
| Thiotepa SCHEMBL20508912 | 0.83 | ABCB11 (1.00) | ABCB11LMNACHRM2CYP3A4ADRA2A | |
| Thiotepa SCHEMBL4760 | 0.83 | ABCB11 (1.00) | ABCB11LMNACHRM2CYP3A4ADRA2A | |
| SCHEMBL31153244 | 0.71 | LMNA (0.73) | ABCB11LMNACHRM2CYP3A4ADRA2A | |
| SCHEMBL535105 | 0.69 | MEN1 (0.46) | LMNA | |
| SCHEMBL3084917 | 0.69 | ABCB11 (0.71) | ABCB11LMNACHRM2CYP3A4ADRA2A | |
| SCHEMBL1276982 | 0.67 | KMT2A (0.50) | LMNA | |
| SCHEMBL434983 | 0.67 | HPGD (0.65) | ABCB11LMNACHRM2CYP3A4ADRA2A | |
| SCHEMBL1276983 | 0.62 | MAPT (0.46) | SMN1; SMN2 | |
| SCHEMBL11392242 | 0.62 | ABCB11 (0.59) | ABCB11LMNACHRM2CYP3A4ADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6221383-B1 | BLEND OF AT LEAST TWO POLYMERS, OR AT LEAST ONE POLYMER AND A SOLUBLE POLYVINYLPYRROLIDONE, IN COMBINATION WITH A DRUG PROVIDES A PRESSURE-SENSITIVE ADHESIVE COMPOSITION FOR A TRANSDERMAL DRUG DELIVERY SYSTEM | NOVEN PHARMACEUTICALS, INC. | 2001-04-24 | — | — | US | disclosed |