Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA5 | P22460 | 3/20 | 1.00 |
| ▸ | KCNH2 | Q12809 | 3/20 | 1.00 |
| ▸ | MAPT | P10636 | 5/20 | 0.81 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.81 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.81 |
| ▸ | TP53 | P04637 | 4/20 | 0.81 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.81 |
| ▸ | HPGD | P15428 | 4/20 | 0.81 |
| ▸ | NPC1 | O15118 | 3/20 | 0.81 |
| ▸ | RAB9A | P51151 | 3/20 | 0.81 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.81 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.81 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.81 |
| ▸ | RELA | Q04206 | 2/20 | 0.81 |
| ▸ | LMNA | P02545 | 2/20 | 0.81 |
| ▸ | THRB | P10828 | 2/20 | 0.81 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.81 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.81 |
| ▸ | CSNK2A2 | P19784 | 3/20 | 0.73 |
| ▸ | CSNK2B | P67870 | 3/20 | 0.73 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 6,4'-Dimethoxyflavone SCHEMBL29478471 | 0.90 | MAPT (1.00) | KCNA5KCNH2MAPTKDM4EALDH1A1 | |
| 6,4'-Dimethoxyflavone SCHEMBL4281291 | 0.90 | MAPT (1.00) | KCNA5KCNH2MAPTKDM4EALDH1A1 | |
| SCHEMBL28154767 | 0.89 | MAOB (0.86) | KCNA5KCNH2MAPTKDM4EALDH1A1 | |
| SCHEMBL10024074 | 0.88 | CSNK2A2 (0.82) | KCNA5KCNH2MAPTKDM4EALDH1A1 | |
| SCHEMBL31238310 | 0.86 | MAPT (0.91) | KCNA5KCNH2MAPTKDM4EALDH1A1 | |
| SCHEMBL4990151 | 0.84 | GABRP (1.00) | KCNA5KCNH2MAPTKDM4EALDH1A1 | |
| SCHEMBL13169617 | 0.84 | MAOB (0.80) | KCNA5KCNH2MAPTKDM4EALDH1A1 | |
| SCHEMBL490928 | 0.84 | MAPT (1.00) | KCNA5KCNH2MAPTKDM4EALDH1A1 | |
| SCHEMBL31675989 | 0.84 | MAPT (1.00) | KCNA5KCNH2MAPTKDM4EALDH1A1 | |
| SCHEMBL4983190 | 0.84 | APP (1.00) | KCNA5KCNH2MAPTKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6872771-B1 | Tire with rubber containing flavone | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2005-03-29 | — | — | US | claimed |
| JP-2003504327-A | — | — | 2003-02-04 | — | — | JP | claimed |
| EP-1223928-A2 | USE OF FLAVONES, COUMARINS AND RELATED COMPOUNDS TO TREAT INFECTIONS | Prendergast, Patrick Thomas (IE) | 2002-07-24 | — | — | EP | claimed |
| WO-2001003681-A2 | USE OF FLAVONES, COUMARINS AND RELATED COMPOUNDS TO TREAT INFECTIONS | PRENDERGAST PATRICK T (IE) | 2001-01-18 | — | — | WO | claimed |
| EP-2863875-B1 | MOUTH RINSE EMULSIONS | PROCTER & GAMBLE (US) | 2018-08-22 | — | — | EP | disclosed |
| EP-2730431-B1 | Rubber composition and tire with rubber containing flavone | GOODYEAR TIRE & RUBBER (US) | 2017-06-28 | — | — | EP | disclosed |
| EP-2863875-A2 | MOUTH RINSE EMULSIONS | The Procter & Gamble Company (US) | 2015-04-29 | — | — | EP | disclosed |
| EP-2415473-B1 | ORAL CARE COMPOSITIONS CONTAINING COMBINATIONS OF ANTI-BACTERIAL AND HOST-RESPONSE MODULATING AGENTS | PROCTER & GAMBLE (US) | 2014-09-17 | — | — | EP | disclosed |
| US-20140135433-A1 | TIRE WITH RUBBER CONTAINING FLAVONE | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2014-05-15 | — | — | US | disclosed |
| EP-2730431-A1 | Rubber composition and tire with rubber containing flavone | The Goodyear Tire & Rubber Company (US) | 2014-05-14 | — | — | EP | disclosed |
| WO-2013192382-A2 | MOUTH RINSE EMULSIONS | THE PROCTER & GAMBLE COMPANY (US) | 2013-12-27 | — | — | WO | disclosed |
| US-20130344120-A1 | Mouth Rinse Emulsions | THE PROCTER & GAMBLE COMPANY | 2013-12-26 | — | — | US | disclosed |
| EP-1391327-A1 | Tire with rubber containing flavone | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2004-02-25 | — | — | EP | disclosed |
| EP-1379524-A2 | CHROMANE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS ANTITUMOR AGENTS | Pharmacia Italia S.p.A. (IT) | 2004-01-14 | — | — | EP | disclosed |
| WO-2003057210-A1 | COMPOSITIONS AND METHODS FOR INCREASING CELL PROLIFERATION COMPRISING A FLAVONOID | KIMBERLY-CLARK WORLDWIDE, INC. (US) | 2003-07-17 | — | — | WO | disclosed |
| US-20030125264-A1 | Methods For Treating Wounds | KIMBERLY-CLARK WORLDWIDE, INC. | 2003-07-03 | — | — | US | disclosed |
| US-6555523-B1 | Such as 3',4'-diacetoxy-5,6,7-trimethoxyflavone or naringin in the treatment HIV, picornavirus, and/or respiratory virus | CASCADE ESTATES LTD. (MU) | 2003-04-29 | — | — | US | disclosed |
| WO-2002070515-A2 | CHROMANE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS ANTITUMOR AGENTS | PHARMACIA ITALIA SPA (IT) | 2002-09-12 | — | — | WO | disclosed |
| EP-1223928-A2 | USE OF FLAVONES, COUMARINS AND RELATED COMPOUNDS TO TREAT INFECTIONS | Prendergast, Patrick Thomas (IE) | 2002-07-24 | — | — | EP | disclosed |
| WO-2001003681-A2 | USE OF FLAVONES, COUMARINS AND RELATED COMPOUNDS TO TREAT INFECTIONS | PRENDERGAST PATRICK T (IE) | 2001-01-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030125264-A1 | Methods For Treating Wounds | FGF2, MMP1, FIBP | KCNA5 4498/4885KCNH2 2555/4885MAPT 4313/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.