Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 1.00 |
| ▸ | MEN1 | O00255 | 5/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 5/20 | 1.00 |
| ▸ | NPC1 | O15118 | 5/20 | 1.00 |
| ▸ | RAB9A | P51151 | 5/20 | 1.00 |
| ▸ | CSNK2A2 | P19784 | 4/20 | 1.00 |
| ▸ | CSNK2B | P67870 | 4/20 | 1.00 |
| ▸ | CSNK2A1 | P68400 | 4/20 | 1.00 |
| ▸ | NFKB1 | P19838 | 2/20 | 1.00 |
| ▸ | NFKB2 | Q00653 | 2/20 | 1.00 |
| ▸ | RELA | Q04206 | 2/20 | 1.00 |
| ▸ | RECQL | P46063 | 1/20 | 1.00 |
| ▸ | TP53 | P04637 | 7/20 | 0.85 |
| ▸ | CYP3A4 | P08684 | 7/20 | 0.85 |
| ▸ | HPGD | P15428 | 5/20 | 0.85 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.85 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.85 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.85 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.85 |
| ▸ | TSHR | P16473 | 2/20 | 0.85 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31675989 | 1.00 | MAPT (1.00) | MAPTMEN1KMT2ANPC1RAB9A | |
| SCHEMBL31238524 | 0.96 | MAPT (0.92) | MAPTMEN1KMT2ANPC1RAB9A | |
| SCHEMBL4650062 | 0.92 | MAPT (1.00) | MAPTMEN1KMT2ANPC1RAB9A | |
| SCHEMBL31675778 | 0.92 | MAPT (1.00) | MAPTMEN1KMT2ANPC1RAB9A | |
| SCHEMBL534596 | 0.89 | CYP3A4 (1.00) | MAPTMEN1KMT2ANPC1RAB9A | |
| SCHEMBL30120666 | 0.89 | CYP3A4 (1.00) | MAPTMEN1KMT2ANPC1RAB9A | |
| 6,4'-Dimethoxyflavone SCHEMBL4281291 | 0.88 | MAPT (1.00) | MAPTMEN1KMT2ANPC1RAB9A | |
| 6,4'-Dimethoxyflavone SCHEMBL29478471 | 0.88 | MAPT (1.00) | MAPTMEN1KMT2ANPC1RAB9A | |
| SCHEMBL31238403 | 0.88 | MAPT (0.92) | MAPTMEN1KMT2ANPC1RAB9A | |
| SCHEMBL311405 | 0.87 | MAPT (1.00) | MAPTMEN1KMT2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 196 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6872771-B1 | Tire with rubber containing flavone | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2005-03-29 | — | — | US | claimed |
| CN-109890376-A | Composition is used in PGC-1 α activation | 三得利控股株式会社 | 2019-06-14 | — | — | CN | disclosed |
| CN-109890378-A | FOXO1 activity-inhibiting composition | 三得利控股株式会社 | 2019-06-14 | — | — | CN | disclosed |
| WO-2019110458-A1 | LIQUID-CRYSTALLINE MEDIUM FOR USE IN A SWITCHING ELEMENT | MERCK PATENT GMBH (DE) | 2019-06-13 | — | — | WO | disclosed |
| EP-2259768-B1 | COMPOSITIONS CONTAINING CYCLIC PEPTIDES AND METHODS OF USE | MERCK PATENT GMBH (DE) | 2019-05-22 | — | — | EP | disclosed |
| US-10278911-B2 | Compositions containing cyclic peptides and methods of use | MERCK PATENT GMBH (DE) | 2019-05-07 | — | — | US | disclosed |
| EP-2553026-B1 | METAL OXIDE PARTICLES AFTER-TREATED WITH ORGANIC PHOSPHORUS COMPOUNDS | MERCK PATENT GMBH (DE) | 2018-03-28 | — | — | EP | disclosed |
| US-9700501-B2 | Use of indole compounds as a cosmetic | MERCK PATENT GMBH (DE) | 2017-07-11 | — | — | US | disclosed |
| EP-2730431-B1 | Rubber composition and tire with rubber containing flavone | GOODYEAR TIRE & RUBBER (US) | 2017-06-28 | — | — | EP | disclosed |
| EP-1660592-B1 | SILICON DIOXIDE-COATED NANOPARTICULATE UV PROTECTANT | MERCK PATENT GMBH (DE) | 2016-10-19 | — | — | EP | disclosed |
| WO-2004033561-A1 | NON-FLAK COATED COLOURING PIGMENT AND METHOD FOR THE PRODUCTION AND USE THEREOF | MERCK PATENT GMBH (DE) | 2004-04-22 | — | — | WO | disclosed |
| US-20040067894-A1 | Preparation having antioxidant properties | MERCK PATENT GMBH (DE) | 2004-04-08 | — | — | US | disclosed |
| US-20040059100-A1 | Process for the preparation of flavone derivatives | EUROPEAN BRAND PARTICIPATIONS SA (LU) | 2004-03-25 | — | — | US | disclosed |
| EP-1400579-A2 | Composition with anti-oxidative properties | MERCK PATENT GmbH (DE) | 2004-03-24 | — | — | EP | disclosed |
| EP-1391327-A1 | Tire with rubber containing flavone | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2004-02-25 | — | — | EP | disclosed |
| EP-1382329-A1 | Compositions for photoprotection comprising a flavonoid | MERCK PATENT GmbH (DE) | 2004-01-21 | — | — | EP | disclosed |
| EP-1355898-A1 | METHOD FOR PRODUCING FLAVONE DERIVATIVES | MERCK PATENT GmbH (DE) | 2003-10-29 | — | — | EP | disclosed |
| WO-2003057210-A1 | COMPOSITIONS AND METHODS FOR INCREASING CELL PROLIFERATION COMPRISING A FLAVONOID | KIMBERLY-CLARK WORLDWIDE, INC. (US) | 2003-07-17 | — | — | WO | disclosed |
| US-20030125264-A1 | Methods For Treating Wounds | KIMBERLY-CLARK WORLDWIDE, INC. | 2003-07-03 | — | — | US | disclosed |
| WO-2002060889-A1 | METHOD FOR PRODUCING FLAVONE DERIVATIVES | MERCK PATENT GMBH (DE) | 2002-08-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040067894-A1 | Preparation having antioxidant properties | GPX1, CBR1, CYC1 | MAPT 4500/4885MEN1 3482/4885KMT2A 4699/4885 |
| US-10278911-B2 | Compositions containing cyclic peptides and methods of use | CUTA, NGLY1, CALCA | MAPT 3896/4885MEN1 1564/4885KMT2A 4725/4885 |
| US-20040059100-A1 | Process for the preparation of flavone derivatives | HK2, MAP2K5, MAP2K4 | MAPT 842/4885MEN1 675/4885KMT2A 611/4885 |
| US-20030125264-A1 | Methods For Treating Wounds | FGF2, MMP1, FIBP | MAPT 4313/4885MEN1 3867/4885KMT2A 4306/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.