Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K4 | O95819 | 1/20 | 0.46 |
| ▸ | CDK8 | P49336 | 1/20 | 0.46 |
| ▸ | CLK2 | P49760 | 1/20 | 0.46 |
| ▸ | CDK7 | P50613 | 1/20 | 0.46 |
| ▸ | CDK9 | P50750 | 1/20 | 0.46 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.46 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.46 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.46 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.46 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.46 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.46 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.42 |
| ▸ | ESR1 | P03372 | 3/20 | 0.39 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.39 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 5/20 | 0.38 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.38 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2224981 | 0.84 | MAP4K4 (0.54) | MAP4K4CDK8CLK2CDK7CDK9 | |
| SCHEMBL18848508 | 0.83 | NOS1 (0.42) | MAP4K4CDK8CLK2CDK7CDK9 | |
| SCHEMBL16962242 | 0.76 | ALDH1A1 (0.50) | PDGFRBPDGFRAPDE3BPDE3AALDH1A1 | |
| SCHEMBL534471 | 0.76 | DYRK1A (0.46) | MAP4K4CDK8CLK2CDK7CDK9 | |
| SCHEMBL1359776 | 0.76 | MAP4K4 (0.46) | MAP4K4CDK8CLK2CDK7CDK9 | |
| SCHEMBL16289378 | 0.76 | MAP4K4 (0.46) | MAP4K4CDK8CLK2CDK7CDK9 | |
| SCHEMBL1360422 | 0.76 | MAP4K4 (0.46) | MAP4K4CDK8CLK2CDK7CDK9 | |
| SCHEMBL5537413 | 0.76 | CYP1A2 (0.57) | MAP4K4CDK8CLK2CDK7CDK9 | |
| SCHEMBL15043760 | 0.76 | ADORA3 (0.39) | DYRK1APDGFRBPDGFRAPDE3BPDE3A | |
| SCHEMBL31419066 | 0.76 | BACE1 (0.41) | DYRK1AALDH1A1MEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8507509-B2 | Saturated and insaturated bi- or tricyclic aryloxyacetamine derivatives and their use as fungicides | SYNGENTA CROP PROTECTION LLC (US) | 2013-08-13 | — | — | US | disclosed |
| CN-101815703-B | Novel fungicides | DEERE & CO | 2013-07-24 | — | — | CN | disclosed |
| CN-103183637-A | Quinoline derivatives and use thereof as fungicides | SYNGENTA CROP PROT INC | 2013-07-03 | — | — | CN | disclosed |
| US-8440595-B2 | Fungicides | SYNGENTA CROP PROTECTION LLC (US) | 2013-05-14 | — | — | US | disclosed |
| CN-101827817-B | Saturated and insaturated bi- or tricyclic aryloxyacetamide derivatives and their use as fungicides | SYNGENTA CROP PROTECTION LLC | 2013-05-08 | — | — | CN | disclosed |
| US-8415272-B2 | Quinoline derivatives and their use as fungicides | SYNGENTA CROP PROTECTION LLC (US) | 2013-04-09 | — | — | US | disclosed |
| EP-2571851-A1 | NOVEL AMIDES AS FUNGICIDES | Syngenta Participations AG (CH) | 2013-03-27 | — | — | EP | disclosed |
| US-20130065922-A1 | NOVEL AMIDES AS FUNGICIDES | SYNGENTA CROP PROTECTION LLC (US) | 2013-03-14 | — | — | US | disclosed |
| US-20130065922-A1 | NOVEL AMIDES AS FUNGICIDES | SYNGENTA CROP PROTECTION LLC (US) | 2013-03-14 | — | — | US | disclosed |
| US-20130065922-A1 | NOVEL AMIDES AS FUNGICIDES | SYNGENTA CROP PROTECTION LLC (US) | 2013-03-14 | — | — | US | disclosed |
| WO-2009087098-A2 | QUINOLINE DERIVATIVES AND THEIR USE AS FUNGICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2009-07-16 | — | — | WO | disclosed |
| EP-2068632-A1 | FUNGICIDES | Syngeta Participations AG (CH) | 2009-06-17 | — | — | EP | disclosed |
| WO-2009049716-A2 | NOVEL FUNGICIDES | SYGENTA PARTICIPATIONS AG (CH) | 2009-04-23 | — | — | WO | disclosed |
| WO-2009030467-A2 | SATURATED AND INSATURATED BI- OR TRICYCLIC ARYLOXYACETAMIDE DERIVATIVES AND THEIR USE AS FUNGICIDES | SYNGENTA PARTICIPATIONS AG, (CH) | 2009-03-12 | — | — | WO | disclosed |
| WO-2008110355-A1 | QUINOLINE DERIVATIVES AS FUNGICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2008-09-18 | — | — | WO | disclosed |
| US-20080171767-A1 | N-substituted-2-alkylthio-2-(substituted aryloxy and heteroaryloxy)alkylamides and their sulphinyl and sulphonyl derivatives such as 2-(3,5-dichlorophenoxy)-2-methylthio-N-2-methylprop-2-yl acetamide; fungal infections of plants | SYNGENTA CROP PROTECTION, INC. (US) | 2008-07-17 | — | — | US | disclosed |
| WO-2008028624-A1 | FUNGICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2008-03-13 | — | — | WO | disclosed |
| CN-101115748-A | Acetamide compounds as fungicides | SYNGENTA PARTICIPATIONS AG (CH) | 2008-01-30 | — | — | CN | disclosed |
| EP-1817309-A1 | ACETAMIDE COMPOUNDS AS FUNGICIDES | Syngeta Participations AG (CH) | 2007-08-15 | — | — | EP | disclosed |
| WO-2006058700-A1 | ACETAMIDE COMPOUNDS AS FUNGICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2006-06-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080171767-A1 | N-substituted-2-alkylthio-2-(substituted aryloxy and heteroaryloxy)alkylamides and their sulphinyl and sulphonyl derivatives such as 2-(3,5-dichlorophenoxy)-2-methylthio-N-2-methylprop-2-yl acetamide; fungal infections of plants | NAT1, DPM1, AADAC | MAP4K4 2387/4885CDK8 1820/4885CLK2 3143/4885 |
| US-20130065922-A1 | NOVEL AMIDES AS FUNGICIDES | CYP51A1, DDT, CYP4X1 | MAP4K4 2993/4885CDK8 2136/4885CLK2 4805/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.