Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 2/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.35 |
| ▸ | MAOA | P21397 | 2/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | KMO | O15229 | 1/20 | 0.32 |
| ▸ | SMO | Q99835 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5351336 | 0.90 | BRD4 (0.40) | GRIN1GRIN2BMAOAMAOBEZH2 | |
| SCHEMBL5351344 | 0.90 | BRD4 (0.40) | GRIN1GRIN2BMAOAMAOBEZH2 | |
| SCHEMBL14437182 | 0.89 | MAOA (0.42) | MAOAMAOBEZH2BRD4CREBBP | |
| SCHEMBL5346418 | 0.89 | GRM2 (0.35) | MAOAMAOBEZH2BRD4CREBBP | |
| SCHEMBL5346415 | 0.89 | GRM2 (0.35) | MAOAMAOBEZH2BRD4CREBBP | |
| SCHEMBL5345167 | 0.84 | GRIN1 (0.35) | GRIN1GRIN2BMAOAMAOB | |
| SCHEMBL5345174 | 0.84 | GRIN1 (0.35) | GRIN1GRIN2BMAOAMAOB | |
| SCHEMBL5345634 | 0.83 | CYP11B2 (0.39) | MAOAMAOBBRD4CREBBP | |
| SCHEMBL5345629 | 0.83 | CYP11B2 (0.39) | MAOAMAOBBRD4CREBBP | |
| SCHEMBL5352491 | 0.79 | MAOA (0.45) | MAOAMAOBEZH2BRD4CREBBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007088478-A1 | INDAZOLE OXAZOLIDINONES AS ANTIBACTERIAL AGENTS | PFIZER PRODUCTS INC. (US) | 2007-08-09 | — | — | WO | disclosed |
| WO-2007088478-A1 | INDAZOLE OXAZOLIDINONES AS ANTIBACTERIAL AGENTS | PFIZER PRODUCTS INC. (US) | 2007-08-09 | — | — | WO | disclosed |