Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 1/20 | 0.53 |
| ▸ | CA12 | O43570 | 2/20 | 0.52 |
| ▸ | CA1 | P00915 | 2/20 | 0.52 |
| ▸ | CA2 | P00918 | 2/20 | 0.52 |
| ▸ | CA7 | P43166 | 2/20 | 0.52 |
| ▸ | CA9 | Q16790 | 2/20 | 0.52 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.52 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.50 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 2/20 | 0.46 |
| ▸ | TYR | P14679 | 2/20 | 0.46 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
| ▸ | CA3 | P07451 | 1/20 | 0.46 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.46 |
| ▸ | CA4 | P22748 | 1/20 | 0.46 |
| ▸ | CA6 | P23280 | 1/20 | 0.46 |
| ▸ | DPP4 | P27487 | 1/20 | 0.46 |
| ▸ | CA5A | P35218 | 1/20 | 0.46 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrangeaic Acid SCHEMBL5352105 | 1.00 | TTR (0.53) | TTRCA12CA1CA2CA7 | |
| Hydrangeaic Acid SCHEMBL12204951 | 1.00 | TTR (0.53) | TTRCA12CA1CA2CA7 | |
| SCHEMBL30477514 | 0.90 | TRPA1 (0.63) | TTRCA12CA1CA2CA7 | |
| SCHEMBL1647970 | 0.90 | TRPA1 (0.63) | TTRCA12CA1CA2CA7 | |
| SCHEMBL21530613 | 0.90 | TRPA1 (0.63) | TTRCA12CA1CA2CA7 | |
| SCHEMBL20594072 | 0.84 | LCK (0.53) | TTRCA12CA1CA2CA7 | |
| SCHEMBL23718096 | 0.81 | KAT8 (0.49) | CA12CA1CA2CA7CA9 | |
| SCHEMBL20333014 | 0.80 | RELA (0.51) | CA12CA1CA2CA7CA9 | |
| SCHEMBL26639076 | 0.80 | RELA (0.51) | CA12CA1CA2CA7CA9 | |
| SCHEMBL26727059 | 0.80 | PTPN1 (0.62) | TTRCA12CA1CA2CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1311258-B1 | COMPOSITIONS CONTAINING HYPOTRIGLYCERIDEMICALLY ACTIVE STILBENOIDS | INSMED INC (US) | 2005-04-06 | — | — | EP | claimed |
| EP-1311258-A2 | COMPOSITIONS CONTAINING HYPOTRIGLYCERIDEMICALLY ACTIVE STILBENOIDS | Insmed Incorporated (US) | 2003-05-21 | — | — | EP | claimed |
| US-6541522-B2 | Including longistyline A-2-carboxylic acid as a dietary supplement | INSMED INCORPORATED | 2003-04-01 | — | — | US | claimed |
| US-20020058708-A1 | Compositions containing hypotriglyceridemically active stilbenoids | SHAMAN PHARMACEUTICALS | 2002-05-16 | — | — | US | claimed |
| US-20020055541-A1 | Compositions containing hypotriglyceridemically active stilbenoids | SHAMAN PHARMACEUTICALS, INC. | 2002-05-09 | — | — | US | claimed |
| WO-2002013806-A2 | COMPOSITIONS CONTAINING HYPOTRIGLYCERIDEMICALLY ACTIVE STILBENOIDS | INSMED INCORPORATED (US) | 2002-02-21 | — | — | WO | claimed |
| WO-2002013809-A2 | COMPOSITIONS CONTAINING HYPOTRIGLYCERIDEMICALLY ACTIVE STILBENOIDS | INSMED INCORPORATED (US) | 2002-02-21 | — | — | WO | claimed |
| US-20130209617-A1 | COMPOSITIONS AND METHODS FOR USE IN PROMOTING PRODUCE HEALTH | PACE INTERNATIONAL, LLC (US) | 2013-08-15 | — | — | US | disclosed |
| US-7163961-B1 | Drugs, foods and oral compositions containing stilbene-type compounds | SUNSTAR INC. (JP) | 2007-01-16 | — | — | US | disclosed |
| EP-1311258-B1 | COMPOSITIONS CONTAINING HYPOTRIGLYCERIDEMICALLY ACTIVE STILBENOIDS | INSMED INC (US) | 2005-04-06 | — | — | EP | disclosed |
| EP-1311258-A2 | COMPOSITIONS CONTAINING HYPOTRIGLYCERIDEMICALLY ACTIVE STILBENOIDS | Insmed Incorporated (US) | 2003-05-21 | — | — | EP | disclosed |
| US-6541522-B2 | Including longistyline A-2-carboxylic acid as a dietary supplement | INSMED INCORPORATED | 2003-04-01 | — | — | US | disclosed |
| US-20020058708-A1 | Compositions containing hypotriglyceridemically active stilbenoids | SHAMAN PHARMACEUTICALS | 2002-05-16 | — | — | US | disclosed |
| US-20020055541-A1 | Compositions containing hypotriglyceridemically active stilbenoids | SHAMAN PHARMACEUTICALS, INC. | 2002-05-09 | — | — | US | disclosed |
| WO-2002013806-A2 | COMPOSITIONS CONTAINING HYPOTRIGLYCERIDEMICALLY ACTIVE STILBENOIDS | INSMED INCORPORATED (US) | 2002-02-21 | — | — | WO | disclosed |
| WO-2002013809-A2 | COMPOSITIONS CONTAINING HYPOTRIGLYCERIDEMICALLY ACTIVE STILBENOIDS | INSMED INCORPORATED (US) | 2002-02-21 | — | — | WO | disclosed |
| EP-1161944-A1 | DRUGS, FOODS AND ORAL COMPOSITIONS CONTAINING STILBENE-TYPE COMPOUNDS | Sunstar Inc. (JP) | 2001-12-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020058708-A1 | Compositions containing hypotriglyceridemically active stilbenoids | CPT1B, CPT1A, LIPC | TTR 1446/4885CA12 4765/4885CA1 4285/4885 |
| US-20020055541-A1 | Compositions containing hypotriglyceridemically active stilbenoids | CPT1B, CPT1A, LIPC | TTR 1446/4885CA12 4765/4885CA1 4285/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.