SCHEMBL5352288

SCHEMBL5352288

CC(=O)N1C(C)(C)CC(CCCCCCCCCCCCN2C(=O)CCC2=O)CC1(C)C

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 3/20 0.38
HTT P42858 2/20 0.38
HPGD P15428 1/20 0.38
CHRM2 P08172 7/20 0.34
CHRM4 P08173 7/20 0.34
CHRM5 P08912 7/20 0.34
CHRM1 P11229 7/20 0.34
CHRM3 P20309 7/20 0.34
ALDH1A1 P00352 1/20 0.34
FAAH O00519 1/20 0.34
MGLL Q99685 1/20 0.34
DRD2 P14416 3/20 0.34
DRD4 P21917 3/20 0.34
DRD3 P35462 3/20 0.34
TSHR P16473 1/20 0.33
POLB P06746 2/20 0.33
ALPL P05186 1/20 0.33
HSD17B10 Q99714 2/20 0.32
KDM4E B2RXH2 1/20 0.32
GAA P10253 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6275548 1.00 SMN1; SMN2 (0.38) SMN1; SMN2HTTHPGDCHRM2CHRM4
SCHEMBL757831 0.85 SMN1; SMN2 (0.37) SMN1; SMN2HTTHPGDCHRM2CHRM4
SCHEMBL1424720 0.84 FAAH (0.38) SMN1; SMN2HTTHPGDCHRM2CHRM4
SCHEMBL701952 0.80
SCHEMBL1535635 0.79 SMN1; SMN2 (0.37) SMN1; SMN2HTTHPGDCHRM2CHRM4
SCHEMBL295613 0.77 CHRM2 (0.37) SMN1; SMN2HTTHPGDCHRM2CHRM4
SCHEMBL9741341 0.70 KMT2A (0.31) KMT2A
SCHEMBL8829438 0.68 MGLL (0.52) SMN1; SMN2HTTHPGDALDH1A1FAAH
SCHEMBL8629340 0.68 MGLL (0.52) SMN1; SMN2HTTHPGDALDH1A1FAAH
SCHEMBL8862703 0.68 MGLL (0.52) SMN1; SMN2HTTHPGDALDH1A1FAAH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7288583-B2 Method of content protection with durable UV absorbers CIBA SPECIALTY CHEMICALS CORPORATION (US) 2007-10-30 US disclosed
US-20050171253-A1 Containers or films comprising hydroxyphenlbenzotriazole uv absorbers for protecting contents against the effects of uv radiation CIBA SPECIALTY CHEMICALS CORP. 2005-08-04 US disclosed
EP-1476503-A1 CONTAINERS OR FILMS COMPRISING HYDROXYPHENYLBENZOTRIAZOLE UV ABSORBERS FOR PROTECTING CONTENTS AGAINST THE EFFECTS OF UV RADIATION Ciba SC Holding AG (CH) 2004-11-17 EP disclosed
US-20040191447-A1 storage of food, beverages, drugs or cosmetics in radiation transparent plastic containers having coatings comprising stabilizer agents selected from hydroxyphenyl benzotriazole ultraviolet radiation absorber materials ANDREWS STEPHEN M (US) 2004-09-30 US disclosed
US-6797751-B2 A CLEAR OR LIGHTLY COLORED PLASTIC CONTAINERS OR FILMS COMPRISING A BENZOTRIAZOLES OR TRIS-ARYL-S-TRIAZINES STABILIZER; PROTECTIVE DEVICES FOR FOODS, BEVERAGES, DRUGS, COSMETICS, SHAMPOO CIBA SPECIALTY CHEMICALS CORPORATION 2004-09-28 US disclosed
US-6746739-B2 A CLEAR OR LIGHTLY COLORED PLASTIC CONTAINERS OR FILMS, COMPRISING BENZOTRIAZOLES AND TRISARYL TRIAZINES; USE FOR FOODSTUFFS, BEVERAGES, PHARMACEUTICALS, COSMETICS, PERSONAL CARE PRODUCTS, SHAMPOOS CIBA SPECIALTY CHEMICALS CORPORATION 2004-06-08 US disclosed
WO-2003070819-A1 CONTAINERS OR FILMS COMPRISING HYDROXYPHENLBENZOTRIAZOLE UV ABSORBERS FOR PROTECTING CONTENTS AGAINST THE EFFECTS OF UV RADIATION CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2003-08-28 WO disclosed
US-20030144389-A1 Method of content protection with durable UV absorbers ANDREWS STEPHEN MARK (US) 2003-07-31 US disclosed
US-20030119950-A1 Method of content protection with durable UV absorbers ANDREWS STEPHEN MARK (US) 2003-06-26 US disclosed
US-20020028861-A1 Method of content protection with durable UV absorbers CIBA SPECIALTY CHEMICALS CORP. 2002-03-07 US disclosed