SCHEMBL757831

SCHEMBL757831

CC1(C)CC(CCCCCCCCCCCCN2C(=O)CCC2=O)CC(C)(C)N1O

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.37
HPGD P15428 1/20 0.37
HTT P42858 1/20 0.37
CHRM2 P08172 9/20 0.36
CHRM4 P08173 9/20 0.36
CHRM5 P08912 9/20 0.36
CHRM1 P11229 9/20 0.36
CHRM3 P20309 9/20 0.36
FAAH O00519 1/20 0.36
MGLL Q99685 1/20 0.36
DRD2 P14416 6/20 0.36
DRD4 P21917 5/20 0.36
DRD3 P35462 5/20 0.36
ALDH1A1 P00352 1/20 0.34
POLB P06746 2/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
TSHR P16473 1/20 0.33
ADRB2 P07550 1/20 0.32
ADRB1 P08588 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1424720 0.88 FAAH (0.38) SMN1; SMN2HPGDHTTCHRM2CHRM4
SCHEMBL5352288 0.85 SMN1; SMN2 (0.38) SMN1; SMN2HPGDHTTCHRM2CHRM4
SCHEMBL6275548 0.85 SMN1; SMN2 (0.38) SMN1; SMN2HPGDHTTCHRM2CHRM4
SCHEMBL295613 0.81 CHRM2 (0.37) SMN1; SMN2HPGDHTTCHRM2CHRM4
SCHEMBL23326466 0.80 GAA (0.41) GAA
SCHEMBL1535635 0.79 SMN1; SMN2 (0.37) SMN1; SMN2HPGDHTTCHRM2CHRM4
SCHEMBL22325703 0.79 FAAH (0.37) SMN1; SMN2HPGDHTTFAAHMGLL
SCHEMBL32682870 0.75 SMN1; SMN2 (0.34) SMN1; SMN2HPGDHTTCHRM2CHRM4
SCHEMBL10135303 0.72 GAA (0.38) GAA
SCHEMBL28996771 0.72 GAA (0.38) GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 183 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8618224-B2 Viscosity breaking process for olefin polymers BASF SE (DE) 2013-12-31 US claimed
US-20130245203-A1 Viscosity Breaking Process for Olefin Polymers BASF SE (DE) 2013-09-19 US claimed
JP-2009527608-A 2009-07-30 JP claimed
EP-1987070-A1 VISCOSITY BREAKING PROCESS FOR OLEFIN POLYMERS Ciba Holding Inc. (CH) 2008-11-05 EP claimed
WO-2007096276-A1 VISCOSITY BREAKING PROCESS FOR OLEFIN POLYMERS CIBA HOLDING INC. (CH) 2007-08-30 WO claimed
US-20070200272-A1 Viscosity breaking process for olefin polymers CIBA SPECIALTY CHEMICALS CORP. 2007-08-30 US claimed
JP-2006522193-A 2006-09-28 JP claimed
US-7084196-B2 Flame retardant compositions CIBA SPECIALTY CHEMICALS CORPORATION (US) 2006-08-01 US claimed
EP-1606372-A1 DIESEL FUEL COMPOSITION AND A METHOD TO IMPROVE FILTERABILITY OF DIESEL FUEL Ciba SC Holding AG (CH) 2005-12-21 EP claimed
EP-1379584-B1 FLAME RETARDANT COMPOSITIONS CIBA SC HOLDING AG (CH) 2005-08-24 EP claimed
EP-1379584-A1 FLAME RETARDANT COMPOSITIONS Ciba Specialty Chemicals Holding Inc. (CH) 2004-01-14 EP claimed
EP-0818526-B1 Stabilizers for the prevention of gum formation in gasoline CIBA SC HOLDING AG (CH) 2003-02-12 EP claimed
WO-2002074847-A1 FLAME RETARDANT COMPOSITIONS CIBA SPECIALITY CHEMICALS HOLDING INC. (CH) 2002-09-26 WO claimed
EP-0988273-B1 POLYMERIZATION INHIBITION OF ACRYLATES USING BLENDS OF NITROXIDES ONDEO NALCO ENERGY SERV LP (US) 2002-09-18 EP claimed
EP-0963971-B1 Method for inhibiting polymer formation in styrene processing NALCO EXXON ENERGY CHEM LP (US) 2001-11-07 EP claimed
WO-2000036052-A1 INHIBITING POLYMERIZATION OF VINYL AROMATIC MONOMERS USING SYNERGISTIC MIXTURES CONTAINING NITROXIDE STABILIZERS NALCO/EXXON ENERGY CHEMICALS, L.P. (CH) 2000-06-22 WO claimed
EP-0794933-B1 A METHOD FOR INHIBITING PREMATURE POLYMERIZATION OF VINYL AROMATIC MONOMERS CIBA SC HOLDING AG (CH) 2000-01-05 EP claimed
US-5711767-A AMINES, PHENOLIC COMPOUNDS AND NITROXIDE CIBA SPECIALTY CHEMICALS CORPORATION (US) 1998-01-27 US claimed
EP-0818526-A1 Stabilizers for the prevention of gum formation in gasoline Ciba SC Holding AG (CH) 1998-01-14 EP claimed
EP-0581737-B1 Inhibiting polymerization of vinyl aromatic monomers CIBA GEIGY AG (CH) 1997-04-23 EP claimed