Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 2/20 | 0.56 |
| ▸ | PI4KA | P42356 | 1/20 | 0.56 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.56 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.56 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.56 |
| ▸ | TNF | P01375 | 1/20 | 0.45 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.45 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | PDE4A | P27815 | 1/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.43 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | DAPK1 | P53355 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21121625 | 0.86 | ADORA2A (0.41) | ADORA2API4KAPI4K2BPI4K2API4KB | |
| SCHEMBL21121744 | 0.86 | SMN1; SMN2 (0.47) | ADORA2API4KAPI4K2BPI4K2API4KB | |
| SCHEMBL21121959 | 0.86 | KCNH2 (0.44) | ADORA2API4KAPI4K2BPI4K2API4KB | |
| SCHEMBL21121674 | 0.86 | ACP1 (0.47) | ADORA2API4KAPI4K2BPI4K2API4KB | |
| SCHEMBL21121650 | 0.85 | ADORA2A (0.40) | ADORA2API4KAPI4K2BPI4K2API4KB | |
| SCHEMBL21121682 | 0.85 | PKM (0.43) | ADORA2API4KAPI4K2BPI4K2API4KB | |
| SCHEMBL21121610 | 0.84 | PKM (0.43) | ADORA2API4KAPI4K2BPI4K2API4KB | |
| SCHEMBL21121839 | 0.83 | L3MBTL1 (0.44) | ADORA2API4KAPI4K2BPI4K2API4KB | |
| SCHEMBL21121702 | 0.83 | ADORA2A (0.40) | ADORA2API4KAPI4K2BPI4K2API4KB | |
| SCHEMBL21121814 | 0.82 | ALDH1A1 (0.47) | ADORA2API4KAPI4K2BPI4K2API4KB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3737683-A1 | INHIBITORS OF LOW MOLECULAR WEIGHT PROTEIN TYROSINE PHOSPHATASE (LMPTP) AND USES THEREOF | Sanford Burnham Prebys Medical Discovery Institute (US) | 2020-11-18 | — | — | EP | claimed |
| US-20200338084-A1 | INHIBITORS OF LOW MOLECULAR WEIGHT PROTEIN TYROSINE PHOSPHATASE (LMPTP) AND USES THEREOF | Sanford Burnham Prebys Medical Discovery Institute | 2020-10-29 | — | — | US | claimed |
| WO-2019136093-A1 | INHIBITORS OF LOW MOLECULAR WEIGHT PROTEIN TYROSINE PHOSPHATASE (LMPTP) AND USES THEREOF | Sanford Burnham Prebys Medical Discovery Institute (US) | 2019-07-11 | — | — | WO | claimed |
| EP-3737683-A1 | INHIBITORS OF LOW MOLECULAR WEIGHT PROTEIN TYROSINE PHOSPHATASE (LMPTP) AND USES THEREOF | Sanford Burnham Prebys Medical Discovery Institute (US) | 2020-11-18 | — | — | EP | disclosed |
| US-20200338084-A1 | INHIBITORS OF LOW MOLECULAR WEIGHT PROTEIN TYROSINE PHOSPHATASE (LMPTP) AND USES THEREOF | Sanford Burnham Prebys Medical Discovery Institute | 2020-10-29 | — | — | US | disclosed |
| WO-2019136093-A1 | INHIBITORS OF LOW MOLECULAR WEIGHT PROTEIN TYROSINE PHOSPHATASE (LMPTP) AND USES THEREOF | Sanford Burnham Prebys Medical Discovery Institute (US) | 2019-07-11 | — | — | WO | disclosed |
| WO-2014083327-A1 | ADENINE DERIVATIVES SUITABLE FOR THE TREATMENT OF (INTER ALIA) MUSCULAR DYSTROPHY | MD PHARMA AB (SE) | 2014-06-05 | — | — | WO | disclosed |
| US-7256326-B2 | Genetic engineering salt tolerance in crop plants | BLUMWALD EDUARDO | 2007-08-14 | — | — | US | disclosed |
| US-7250560-B2 | Increasing salt tolerance in plants by overexpression of vacuolar NA+/H+ transporters | BLUMWALD EDUARDO | 2007-07-31 | — | — | US | disclosed |
| US-7244878-B2 | Increasing salt tolerance in plants by overexpression of vacuolar Na+ /H+ transporters | BLUMWALD EDUARDO | 2007-07-17 | — | — | US | disclosed |
| US-7041875-B1 | Genetic engineering salt tolerance in crop plants | BLUMWALD EDUARDO | 2006-05-09 | — | — | US | disclosed |
| US-5831092-A | Process for producing purine derivatives | AJINOMOTO CO., INC. (JP) | 1998-11-03 | — | — | US | disclosed |
| US-5750871-A | CULTURE PRODUCT | CALGENE, INC. (US) | 1998-05-12 | — | — | US | disclosed |
| EP-0728757-A1 | Process for producing purine derivatives | Ajinomoto Co., Inc. (JP) | 1996-08-28 | — | — | EP | disclosed |
| US-5463174-A | Expression cassette; oncogene-free cells; capable of regeneration to morphologically normal whole plants | CALGENE INC. (US) | 1995-10-31 | — | — | US | disclosed |
| EP-0270615-B1 | TRANSFORMATION AND FOREIGN GENE EXPRESSION IN $i(BRASSICA) SPECIES | CALGENE, INC. (US) | 1993-08-04 | — | — | EP | disclosed |
| US-5188958-A | Genetically engineered cells capable of regenerating normal whole plants with altered phenotypes | CALGENE, INC. (US) | 1993-02-23 | — | — | US | disclosed |
| EP-0270615-A4 | TRANSFORMATION AND FOREIGN GENE EXPRESSION IN -i(BRASSICA) SPECIES. | CALGENE INC (US) | 1989-11-07 | — | — | EP | disclosed |
| EP-0270615-A1 | TRANSFORMATION AND FOREIGN GENE EXPRESSION IN -i(BRASSICA) SPECIES. | CALGENE INC (US) | 1988-06-15 | — | — | EP | disclosed |
| WO-1987007299-A1 | TRANSFORMATION AND FOREIGN GENE EXPRESSION IN BRASSICA SPECIES | CALGENE, INC. (US) | 1987-12-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200338084-A1 | INHIBITORS OF LOW MOLECULAR WEIGHT PROTEIN TYROSINE PHOSPHATASE (LMPTP) AND USES THEREOF | ACP1, PTPRCAP, PTPRO | ADORA2A 4746/4885PI4KA 148/4885PI4K2B 134/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.