Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP5 | Q01469 | 3/20 | 0.46 |
| ▸ | FABP7 | O15540 | 2/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MDM4 | O15151 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9073538 | 0.87 | FABP5 (0.44) | FABP5FABP7EPHX2KMT2ACA1 | |
| SCHEMBL7198199 | 0.84 | KMT2A (0.41) | FABP5FABP7EPHX2KMT2ACA1 | |
| SCHEMBL7632240 | 0.84 | KMT2A (0.41) | FABP5FABP7EPHX2KMT2ACA1 | |
| SCHEMBL29811163 | 0.84 | KMT2A (0.45) | FABP5FABP7EPHX2KMT2ACA1 | |
| SCHEMBL31671081 | 0.81 | KMT2A (0.49) | FABP5FABP7EPHX2KMT2ACA1 | |
| SCHEMBL12451167 | 0.79 | KMT2A (0.49) | FABP5FABP7EPHX2KMT2ACA1 | |
| SCHEMBL29624561 | 0.78 | KMT2A (0.50) | FABP5FABP7EPHX2KMT2ACASP3 | |
| SCHEMBL29624551 | 0.78 | KMT2A (0.50) | FABP5FABP7EPHX2KMT2ACASP3 | |
| SCHEMBL30594467 | 0.78 | KMT2A (0.50) | FABP5FABP7EPHX2KMT2ACASP3 | |
| SCHEMBL7401413 | 0.78 | KMT2A (0.50) | FABP5FABP7EPHX2KMT2ACASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7300934-B2 | Benzamide nitriles | ROCHE PALO ALTO LLC (US) | 2007-11-27 | — | — | US | disclosed |
| US-20040248949-A1 | Benzamide nitriles | ROCHE PALO ALTO LLC | 2004-12-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040248949-A1 | Benzamide nitriles | CTSK, CTSS, CMA1 | FABP5 3460/4885FABP7 3192/4885EPHX2 4214/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.