SCHEMBL6537098

SCHEMBL6537098

Cc1ccc(S)c(CS)c1

nearest known ligand 0.42

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 2/20 0.42
TAAR1 Q96RJ0 1/20 0.39
AMY1A P0DUB6 1/20 0.36
CYP2A6 P11509 4/20 0.36
CYP1A2 P05177 4/20 0.36
TDP1 Q9NUW8 5/20 0.36
TP53 P04637 2/20 0.32
CYP3A4 P08684 1/20 0.32
THRB P10828 1/20 0.32
ALOX15 P16050 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
TRPA1 O75762 1/20 0.32
ACHE P22303 2/20 0.32
ALDH1A1 P00352 1/20 0.31
PSMD14 O00487 2/20 0.31
COPS5 Q92905 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18231539 0.81 MAPT (0.39) TAAR1AMY1ACYP2A6CYP1A2TDP1
SCHEMBL2100606 0.81 IDO1 (0.42) IDO1TAAR1AMY1ACYP2A6CYP1A2
SCHEMBL14194626 0.80 IDO1 (0.46) IDO1TAAR1AMY1ACYP2A6CYP1A2
SCHEMBL27628977 0.79 AMY1A (0.39) TAAR1AMY1ACYP2A6CYP1A2TDP1
SCHEMBL5352730 0.78 TAAR1 (0.56) IDO1TAAR1AMY1ACYP2A6CYP1A2
SCHEMBL6299443 0.76 TAAR1 (0.39) TAAR1AMY1ACYP2A6CYP1A2TDP1
SCHEMBL29644918 0.76 L3MBTL1 (0.40) TAAR1TP53SMN1; SMN2ALDH1A1
SCHEMBL24073162 0.74 IDO1 (0.41) IDO1TAAR1AMY1ACYP2A6CYP1A2
SCHEMBL3852993 0.74 TAAR1 (0.42) IDO1TAAR1AMY1ACYP2A6CYP1A2
SCHEMBL14599886 0.74 AMY1A (0.59) IDO1AMY1ATDP1TP53ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6791338-B1 Gated nanoscale switch having channel of molecular wires HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. 2004-09-14 US disclosed