Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | PDE4A | P27815 | 3/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.40 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TNF | P01375 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1383429 | 0.87 | POLB (0.42) | POLBPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL454595 | 0.77 | TNF (0.44) | POLBKDM4EMAPTGAAMAPK1 | |
| SCHEMBL5831954 | 0.76 | TDP1 (0.35) | POLBKDM4EMAPTGAAMAPK1 | |
| SCHEMBL11142464 | 0.74 | MAPT (0.49) | POLBKDM4EMAPTGAAMAPK1 | |
| Hydrochloric Acid SCHEMBL11140483 | 0.73 | GAA (0.51) | POLBKDM4EMAPTGAAMAPK1 | |
| SCHEMBL8031008 | 0.73 | TSHR (0.39) | POLBKDM4EMAPTGAAMAPK1 | |
| SCHEMBL28088166 | 0.72 | TNF (0.40) | POLBKDM4EL3MBTL1MEN1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL9793148 | 0.72 | TSHR (0.38) | POLBKDM4EMAPTGAAMAPK1 | |
| SCHEMBL3855076 | 0.71 | RAD52 (0.47) | POLBKDM4EMAPTGAAMAPK1 | |
| Hydrochloric Acid SCHEMBL11143842 | 0.70 | KDM4E (0.46) | POLBKDM4EMAPTGAAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1468049-B1 | YELLOW CATIONIC DYES FOR DYING OF ORGANIC MATERIAL | BASF SE (DE) | 2013-08-14 | — | — | EP | disclosed |
| US-7258702-B2 | Yellow cationic dyes for dyeing of organic material | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2007-08-21 | — | — | US | disclosed |
| EP-1483334-B1 | PROCESS FOR EXCHANGING THE ANIONS OF CATIONIC DYES | CIBA SC HOLDING AG (CH) | 2007-07-04 | — | — | EP | disclosed |
| US-7232467-B2 | Dyeing hair with capped diazonium compound; intense, striking coloration; light, shampoo and rub fastness; storage stability; nondamaging, nonstaining | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2007-06-19 | — | — | US | disclosed |
| US-7229479-B2 | Method of coloring porous material | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2007-06-12 | — | — | US | disclosed |
| US-7223295-B2 | Dyeing hair with capped diazonium compound; intense, striking coloration; light, shampoo and rub fastness; storage stability; nondamaging, nonstaining | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2007-05-29 | — | — | US | disclosed |
| US-7192453-B2 | Method of coloring keratin-containing fibres using diazonium salts | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2007-03-20 | — | — | US | disclosed |
| US-7166710-B2 | Cationic dimeric dyes | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2007-01-23 | — | — | US | disclosed |
| US-7166711-B2 | Cationic dyes | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2007-01-23 | — | — | US | disclosed |
| US-7091358-B2 | Cationic substituted hydrazone dyes | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2006-08-15 | — | — | US | disclosed |
| US-20040158937-A1 | Cationic substituted hydrazone dyes | CIBA SPECIALTY CHEMICALS CORP. | 2004-08-19 | — | — | US | disclosed |
| EP-1438006-A1 | METHOD OF COLOURING KERATIN-CONTAINING FIBRES USING DIAZONIUM SALTS | Ciba SC Holding AG (CH) | 2004-07-21 | — | — | EP | disclosed |
| EP-1430102-A1 | CATIONIC REACTIVE DYES | Ciba SC Holding AG (CH) | 2004-06-23 | — | — | EP | disclosed |
| WO-2004019897-A1 | METHOD OF COLOURING POROUS MATERIAL | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2004-03-11 | — | — | WO | disclosed |
| WO-2004019896-A1 | METHOD OF COLOURING POROUS MATERIAL | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2004-03-11 | — | — | WO | disclosed |
| WO-2003076518-A2 | PROCESS FOR EXCHANGING THE ANIONS OF CATIONIC COMPOUNDS | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2003-09-18 | — | — | WO | disclosed |
| WO-2003070207-A1 | METHOD OF COLOURING KERATIN-CONTAINING FIBRES | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2003-08-28 | — | — | WO | disclosed |
| WO-2003060015-A1 | YELLOW CATIONIC DYES FOR DYING OF ORGANIC MATERIAL | CIBA SPECIALITY CHEMICALS HOLDING INC. (CH) | 2003-07-24 | — | — | WO | disclosed |
| WO-2003032939-A1 | METHOD OF COLOURING KERATIN-CONTAINING FIBRES USING DIAZONIUM SALTS | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2003-04-24 | — | — | WO | disclosed |
| WO-2003029359-A1 | CATIONIC REACTIVE DYES | CIBA SPECIALTY CHEMICALS HOLDINGS INC. (CH) | 2003-04-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040158937-A1 | Cationic substituted hydrazone dyes | KRT18, CYC1, COL1A1 | POLB 2306/4885PDE4A 3914/4885PDE4B 4308/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.