Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNF | P01375 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | GBA1 | P04062 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.33 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.33 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.33 |
| ▸ | PDE5A | O76074 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL454595 | 0.87 | TNF (0.44) | TNFPOLBHTTGBA1KDM4E | |
| SCHEMBL27940328 | 0.85 | ALDH1A1 (0.38) | HTTKDM4ETSHRALDH1A1MEN1 | |
| SCHEMBL2326696 | 0.77 | BMPR1B (0.41) | TNFPOLBHTTGBA1KDM4E | |
| SCHEMBL3971880 | 0.72 | HMGCR (0.44) | TNFHTTGBA1KDM4EGLA | |
| SCHEMBL5352795 | 0.72 | POLB (0.40) | TNFPOLBKDM4ETSHRL3MBTL1 | |
| SCHEMBL687380 | 0.71 | TUBB4A (0.40) | TNFPOLBHTTGBA1KDM4E | |
| Hydrochloric Acid SCHEMBL9192756 | 0.70 | TUBB4A (0.43) | TNFHTTKDM4EGLATSHR | |
| SCHEMBL5176527 | 0.69 | KDM4E (0.41) | TNFPOLBHTTKDM4EGLA | |
| SCHEMBL11822323 | 0.69 | MAPT (0.58) | POLBHTTKDM4ETSHRL3MBTL1 | |
| SCHEMBL2434485 | 0.69 | ALDH1A1 (0.57) | GBA1KDM4ETSHRL3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102858944-B | Delivery of particles | 宝洁公司 | 2016-08-24 | — | — | CN | disclosed |