Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | MGAM | O43451 | 1/20 | 0.56 |
| ▸ | SI | P14410 | 1/20 | 0.56 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.56 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL70685 | 0.82 | — | — | |
| SCHEMBL11781367 | 0.81 | FAAH (0.53) | GAAMCL1ALDH1A1HPGDTSHR | |
| SCHEMBL5353921 | 0.80 | MCL1 (0.44) | GAAMGAMSIMGAM2MCL1 | |
| SCHEMBL6750259 | 0.80 | — | — | |
| Ammonia Solution, Strong SCHEMBL8823685 | 0.80 | — | — | |
| Hydrochloric Acid SCHEMBL25408509 | 0.80 | — | — | |
| SCHEMBL3370470 | 0.80 | — | — | |
| SCHEMBL28807956 | 0.80 | MGAM (0.50) | GAAMGAMSIMGAM2MCL1 | |
| SCHEMBL5395125 | 0.80 | GAA (0.52) | GAAMGAMSIMGAM2KDM4E | |
| SCHEMBL155563 | 0.79 | GAA (0.78) | GAAMGAMSIMGAM2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109651424-B | Synthesis method of 7-protecting group-4- (1-hydrogen-pyrazol-4-yl) pyrrole [2,3-d ] pyrimidine | 新发药业有限公司 | 2021-01-22 | — | — | CN | claimed |
| CN-121758322-A | New synthesis process of (R) - (-) -4-cyano-3-hydroxybutyric acid ethyl ester | 福建永晶科技股份有限公司 | 2026-03-31 | — | — | CN | disclosed |
| CN-117700337-A | Preparation method of high-purity ethyl 2-cyano acetoacetate | 安徽金禾化学材料研究所有限公司 | 2024-03-15 | — | — | CN | disclosed |
| CN-111909137-B | Pyridazinone derivative and application thereof | 深圳微芯生物科技股份有限公司 | 2023-05-30 | — | — | CN | disclosed |
| CN-114437034-A | Pharmaceutical salt and crystal form of phthalazine compound and preparation method thereof | 深圳微芯生物科技股份有限公司 | 2022-05-06 | — | — | CN | disclosed |
| CN-114437042-A | Crystal form of phthalazine compound and preparation method thereof | 深圳微芯生物科技股份有限公司 | 2022-05-06 | — | — | CN | disclosed |
| CN-109651424-B | Synthesis method of 7-protecting group-4- (1-hydrogen-pyrazol-4-yl) pyrrole [2,3-d ] pyrimidine | 新发药业有限公司 | 2021-01-22 | — | — | CN | disclosed |
| WO-2020228577-A1 | PYRIDAZINONE DERIVATIVE AND USE THEREOF | 深圳微芯生物科技股份有限公司 | 2020-11-19 | — | — | WO | disclosed |
| CN-111909137-A | Pyridazinone derivative and application thereof | 深圳微芯生物科技股份有限公司 | 2020-11-10 | — | — | CN | disclosed |
| US-7172894-B2 | Reductase gene and use of the same | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 2007-02-06 | — | — | US | disclosed |
| EP-1201647-B1 | Process for producing 4-cyano-4oxobutanoate and 4-cyano-3-hydroxybutanoate | SUMITOMO CHEMICAL CO (JP) | 2004-09-22 | — | — | EP | disclosed |
| US-20040171119-A1 | Reductase gene and use of the same | SUMITOMO CHEMICAL COMPANY, LIMITED | 2004-09-02 | — | — | US | disclosed |
| EP-1452588-A1 | Reductase gene and use of the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2004-09-01 | — | — | EP | disclosed |
| US-6781009-B2 | BY REACTING A 4-HALO-3-OXOBUTANOATE WITH AN ALKALINE METAL CYANIDE IN METHANOL; PRODUCING 4-CYANO-3-HYDROXYBUTANOATE THEREFROM | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2004-08-24 | — | — | US | disclosed |
| US-20030105347-A1 | Method for producing 4-cyano-3-oxobutanoate and 4-ctano-3-hydroxybutanoate | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2003-06-05 | — | — | US | disclosed |
| EP-1201647-A2 | Process for producing 4-cyano-4oxobutanoate and 4-cyano-3-hydroxybutanoate | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2002-05-02 | — | — | EP | disclosed |
| US-4133827-A | Process for the production of α-cyano-γ-haloacetoacetic compounds | LONZA LTD. (CH) | 1979-01-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030105347-A1 | Method for producing 4-cyano-3-oxobutanoate and 4-ctano-3-hydroxybutanoate | HADHB, HAO2, HAAO | GAA 715/4885MGAM 64/4885SI 616/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.