Sugi Predict

Sugi Predict / Compounds / SCHEMBL5353393

SCHEMBL5353393

SCHEMBL5353393

CCCCCc1ccc(-c2cccc3c2C=C(CC)C3[Zr](Cl)(Cl)(C2C(CC)=Cc3c(-c4ccc(CCCCC)cc4)cccc32)[SiH](C)C)cc1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ HSD11B1 P28845 3/20 0.35
▸ RARB P10826 7/20 0.34
▸ ALDH1A1 P00352 2/20 0.34
▸ MEN1 O00255 1/20 0.34
▸ RARA P10276 1/20 0.34
▸ MAPT P10636 1/20 0.34
▸ MTOR P42345 1/20 0.34
▸ KMT2A Q03164 1/20 0.34
▸ HRH3 Q9Y5N1 1/20 0.33
▸ HSD17B10 Q99714 2/20 0.32
▸ TSHR P16473 1/20 0.32
▸ TLR8 Q9NR97 1/20 0.31
▸ SLC6A2 P23975 2/20 0.31
▸ HTR2C P28335 2/20 0.31
▸ SLC6A4 P31645 2/20 0.31
▸ DRD2 P14416 1/20 0.31
▸ HTR2A P28223 1/20 0.31
▸ KDM4E B2RXH2 1/20 0.31
▸ LMNA P02545 1/20 0.31
▸ ESR1 P03372 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5351443 0.99 RARB (0.36) HSD11B1RARBALDH1A1MEN1RARA
SCHEMBL5351724 0.97 RARB (0.33) HSD11B1RARB
SCHEMBL2518430 0.94 RARB (0.36) HSD11B1RARBALDH1A1MEN1RARA
SCHEMBL2511689 0.93 RARB (0.36) HSD11B1RARBALDH1A1MEN1RARA
SCHEMBL2518453 0.93 RARB (0.36) HSD11B1RARBALDH1A1MEN1RARA
SCHEMBL2513798 0.93 RARB (0.36) HSD11B1RARBALDH1A1MEN1RARA
SCHEMBL5350927 0.92 — —
SCHEMBL2508943 0.91 RARB (0.34) HSD11B1RARBALDH1A1MEN1RARA
SCHEMBL2515731 0.90 GPR3 (0.32) HSD11B1RARBALDH1A1MEN1RARA
SCHEMBL2513773 0.90 RARB (0.33) HSD11B1RARBALDH1A1MEN1RARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1053263-B1 CATALYST SYSTEM BASELL POLYOLEFINE GMBH (DE) 2003-10-01 — — EP claimed
EP-1054911-B1 CATALYST SYSTEM, METHOD FOR THE PRODUCTION THEREOF AND ITS USE FOR THE POLYMERIZATION OF OLEFINS BASELL POLYOLEFINE GMBH (DE) 2003-01-22 — — EP claimed
US-6482902-B1 Catalyst system TARGOR GMBH (DE) 2002-11-19 — — US claimed
US-6350830-B1 SUPPORTED POLYMERIZATION CATALYSTS TAGOR GMBH (DE) 2002-02-26 — — US claimed
US-7202190-B1 Supported catalyst system for the polymerization of olefins TARGOR GMBH (DE) 2007-04-10 — — US disclosed
US-7101940-B2 Chemical compound, method for the production thereof and its use in catalyst systems for producing polyolefins BASELL POLYOLEFINE GMBH (DE) 2006-09-05 — — US disclosed
US-7034173-B2 Chemical products suited for use as co-catalysts, method for the preparation thereof and their use in catalyst systems for producing polyolefins BASELL POLYOLEFINE GMBH (DE) 2006-04-25 — — US disclosed
US-6953829-B2 Catalyst system and the use thereof BASELL POLYOLEFINE GMBH (DE) 2005-10-11 — — US disclosed
US-6949614-B1 Catalyst system BASELL POLYOLEFINE GMBH (DE) 2005-09-27 — — US disclosed
US-6900343-B1 Method for the purification of metallocenes BASELL POLYOLEFINE GMBH (DE) 2005-05-31 — — US disclosed
US-6861384-B2 Process for preparation of a salt-like chemical compound and its use in catalyst systems for preparing polyolefins BASELL POLYOLEFINE GMBH (DE) 2005-03-01 — — US disclosed
US-20040072975-A1 Salt-like chemical compound, its preparation and its use in catalyst systems for preparing polyolefins BASELL POLYPROPYLEN GMBH (DE) 2004-04-15 — — US disclosed
US-20030109652-A1 Catalyst system BOHNEN HANS (DE) 2003-06-12 — — US disclosed
US-6576723-B1 Coordination catalyst comprising metallocene, organoboroaluminum, Lewis base and organometallic compound BASELL POLYOLEFINE GMBH (DE) 2003-06-10 — — US disclosed
US-20030069426-A1 Saline chemical composition, method for producing the same and the use thereof in catalyst systems for producing polyolefins SCHOTTEK JORG (DE) 2003-04-10 — — US disclosed
US-20030013913-A1 Chemical compound, method for the production thereof and its use in catalyst systems for producing polyolefins EQUISTAR CHEMICALS, LP 2003-01-16 — — US disclosed
US-20030008984-A1 Novel catalyst system and the use thereof BASELL POLYOLEFINE GMBH (DE) 2003-01-09 — — US disclosed
US-6500908-B1 ORGANOBORON-ALUMINUM COMPOUND, METALLOCENE, COCATALYTICALLY ACTIVE COMPOUND; BIS(DIMETHYLALUMINOXY)PENTAFLUOROPHENYLBORANE; OLEFIN POLYMERIZATION CATALYST BASELL POLYOLEFINE GMBH (DE) 2002-12-31 — — US disclosed
US-6417302-B1 REACTION PRODUCT OF DI(PENTAFLUOROPHENYL) BORINIC ACID AND ORGANOALUMINUM COMPOUND; OLEFIN POLYMERIZATION COORDINATION CATALYSTS BASELL POLYOLEFINE GMBH (DE) 2002-07-09 — — US disclosed
US-6350830-B1 SUPPORTED POLYMERIZATION CATALYSTS TAGOR GMBH (DE) 2002-02-26 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030069426-A1 Saline chemical composition, method for producing the same and the use thereof in catalyst systems for producing polyolefins CLIC1, HACL2, ADH1C HSD11B1 590/4885RARB 2760/4885ALDH1A1 1603/4885
US-20030013913-A1 Chemical compound, method for the production thereof and its use in catalyst systems for producing polyolefins SCO2, CNOT1, CYC1 HSD11B1 225/4885RARB 2847/4885ALDH1A1 1134/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.