Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 13/20 | 0.44 |
| ▸ | PPARD | Q03181 | 11/20 | 0.44 |
| ▸ | PPARG | P37231 | 7/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | ACACB | O00763 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MC4R | P32245 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5353768 | 0.87 | PPARA (0.43) | PPARAPPARDPPARGCNR1ACACB | |
| SCHEMBL5351942 | 0.81 | PPARA (0.47) | PPARAPPARDPPARGL3MBTL1CNR1 | |
| SCHEMBL14399164 | 0.78 | PPARD (0.43) | PPARAPPARDCNR1ACACB | |
| SCHEMBL5329725 | 0.76 | TPH1 (0.40) | PPARAPPARDPPARGCNR1ACACB | |
| SCHEMBL5324085 | 0.74 | PPARA (0.48) | PPARAPPARDPPARGSMN1; SMN2L3MBTL1 | |
| SCHEMBL14399420 | 0.73 | PPARA (0.47) | PPARAPPARDPPARGSMN1; SMN2L3MBTL1 | |
| SCHEMBL5325989 | 0.73 | PPARA (0.47) | PPARAPPARDPPARGSMN1; SMN2L3MBTL1 | |
| SCHEMBL5330018 | 0.72 | PPARA (0.47) | PPARAPPARDPPARGSMN1; SMN2L3MBTL1 | |
| SCHEMBL5325952 | 0.72 | PPARA (0.51) | PPARAPPARDPPARGCNR1MC4R | |
| SCHEMBL5326681 | 0.70 | CNR1 (0.48) | PPARAPPARDPPARGSMN1; SMN2CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007118963-A2 | SUBSTITUTED N-(PHENETHYL)BENZAMIDE DERIVATIVES, PREPARATION AND USES THEREOF | GENFIT (FR) | 2007-10-25 | — | — | WO | disclosed |