Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 9/20 | 0.43 |
| ▸ | PPARD | Q03181 | 7/20 | 0.43 |
| ▸ | LIPG | Q9Y5X9 | 8/20 | 0.41 |
| ▸ | ACACB | O00763 | 2/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 3/20 | 0.39 |
| ▸ | LIPC | P11150 | 3/20 | 0.38 |
| ▸ | LPL | P06858 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14399164 | 0.91 | PPARD (0.43) | PPARAPPARDLIPGACACBCNR1 | |
| SCHEMBL5324085 | 0.88 | PPARA (0.48) | PPARAPPARDACACBCNR1PPARG | |
| SCHEMBL14399420 | 0.87 | PPARA (0.47) | PPARAPPARDCNR1PPARG | |
| SCHEMBL5325989 | 0.87 | PPARA (0.47) | PPARAPPARDCNR1PPARG | |
| SCHEMBL5353765 | 0.87 | PPARA (0.44) | PPARAPPARDACACBCNR1PPARG | |
| SCHEMBL5329725 | 0.86 | TPH1 (0.40) | PPARAPPARDACACBCNR1PPARG | |
| SCHEMBL5325952 | 0.85 | PPARA (0.51) | PPARAPPARDCNR1PPARG | |
| SCHEMBL5326681 | 0.81 | CNR1 (0.48) | PPARAPPARDACACBCNR1PPARG | |
| SCHEMBL5330018 | 0.81 | PPARA (0.47) | PPARAPPARDCNR1PPARG | |
| SCHEMBL5329478 | 0.80 | PPARA (0.54) | PPARAPPARDCNR1PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007118963-A2 | SUBSTITUTED N-(PHENETHYL)BENZAMIDE DERIVATIVES, PREPARATION AND USES THEREOF | GENFIT (FR) | 2007-10-25 | — | — | WO | disclosed |