SCHEMBL5354762

SCHEMBL5354762

CC(C)(C)c1ccccc1N=CCc1cccc(CC=Nc2ccccc2C(C)(C)C)n1

nearest known ligand 0.47

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.47
PLA2G1B P04054 1/20 0.47
MAPT P10636 1/20 0.47
ATG4B Q9Y4P1 1/20 0.47
GRIN2D O15399 1/20 0.34
GRIN3B O60391 1/20 0.34
GRIN1 Q05586 1/20 0.34
GRIN2A Q12879 1/20 0.34
GRIN2B Q13224 1/20 0.34
GRIN2C Q14957 1/20 0.34
GRIN3A Q8TCU5 1/20 0.34
SIGMAR1 Q99720 1/20 0.34
CA2 P00918 1/20 0.32
TSHR P16473 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
ALOX12 P18054 1/20 0.31
KCNH2 Q12809 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL39595 0.97 ALDH1A1 (0.45) ALDH1A1PLA2G1BMAPTATG4BGRIN2D
SCHEMBL21239492 0.84 NOS3 (0.36) ALDH1A1PLA2G1BMAPTATG4BGRIN2D
SCHEMBL5362668 0.79 CYP2C9 (0.47) ALDH1A1MAPTSIGMAR1TDP1KCNH2
Hydrochloric Acid SCHEMBL7095603 0.76 CYP2C9 (0.45) ALDH1A1MAPTTDP1KCNH2
SCHEMBL6062806 0.76 CYP3A4 (0.38) ALDH1A1GRIN2DGRIN3BGRIN1GRIN2A
Hydrochloric Acid SCHEMBL40278 0.76 BACE1 (0.33)
SCHEMBL21239558 0.76 L3MBTL1 (0.43) ALDH1A1MAPTGRIN2DGRIN3BGRIN1
SCHEMBL21239580 0.76 MAPT (0.41) ALDH1A1MAPTGRIN2DGRIN3BGRIN1
SCHEMBL6061919 0.75 NOS3 (0.37) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL21239586 0.74 CYP3A4 (0.46) ALDH1A1GRIN2DGRIN3BGRIN1GRIN2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7238764-B2 Process for the co-oligomerisation of ethylene and alpha olefins SHELL OIL COMPANY (US) 2007-07-03 US disclosed
US-20050059786-A1 Process for the co-oligomerisation of ethylene and alpha olefins DE BOER ERIC JOHANNES MARIA (NL) 2005-03-17 US disclosed