Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1B | Q00975 | 4/20 | 0.46 |
| ▸ | CTSS | P25774 | 6/20 | 0.42 |
| ▸ | CTSK | P43235 | 5/20 | 0.42 |
| ▸ | CTSL | P07711 | 3/20 | 0.42 |
| ▸ | CTSB | P07858 | 1/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.39 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.37 |
| ▸ | REN | P00797 | 2/20 | 0.37 |
| ▸ | PSMB8 | P28062 | 2/20 | 0.36 |
| ▸ | PSMB9 | P28065 | 2/20 | 0.36 |
| ▸ | PSMB10 | P40306 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5349098 | 0.80 | CACNA1B (0.51) | CACNA1BCTSSCTSKCTSLCTSB | |
| SCHEMBL5351306 | 0.77 | CTSS (0.48) | CACNA1BCTSSCTSKCTSLCTSB | |
| SCHEMBL5351826 | 0.76 | CACNA1B (0.43) | CACNA1BCTSSCTSKCTSLCTSB | |
| SCHEMBL5355126 | 0.75 | MAPK14 (0.42) | CACNA1BCTSSCTSKCTSLREN | |
| SCHEMBL5355122 | 0.75 | CACNA1B (0.45) | CACNA1BCTSSCTSKCTSLREN | |
| SCHEMBL9089830 | 0.73 | CTSS (0.56) | CTSSCTSKCTSLAAK1 | |
| SCHEMBL27539175 | 0.73 | CTSS (0.56) | CTSSCTSKCTSLAAK1 | |
| SCHEMBL28695448 | 0.72 | ACE (0.54) | CTSSCTSKCTSLCTSB | |
| SCHEMBL28713500 | 0.72 | ACE (0.54) | CTSSCTSKCTSLCTSB | |
| SCHEMBL5351397 | 0.71 | CTSK (0.49) | CACNA1BCTSSCTSKCTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7166590-B2 | Amino acid derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 2007-01-23 | — | — | US | disclosed |
| US-20030013725-A1 | Amino acid derivatives | ONO PHARMACEUTICAL CO., LTD. | 2003-01-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030013725-A1 | Amino acid derivatives | CACNA1B, SCN1A, SCN2A | CACNA1B 1/4885CTSS 1885/4885CTSK 3691/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.