Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | CTSK | P43235 | 2/20 | 0.40 |
| ▸ | MGAM | O43451 | 1/20 | 0.39 |
| ▸ | SI | P14410 | 1/20 | 0.39 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.37 |
| ▸ | PGR | P06401 | 1/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15228762 | 0.83 | GAA (0.50) | GAACYP1A2CYP2C9CYP2C19HTT | |
| SCHEMBL7557516 | 0.81 | MAPT (0.44) | GAAKMT2ACTSKMEN1ALDH1A1 | |
| SCHEMBL27527957 | 0.81 | CYP1A2 (0.55) | GAAPOLBCYP1A2SMYD3CYP2C9 | |
| SCHEMBL7425805 | 0.80 | HSP90AA1 (0.47) | KMT2ACTSKMEN1ALDH1A1 | |
| SCHEMBL25827510 | 0.79 | GAA (0.54) | GAACYP2C19KMT2AMEN1ALDH1A1 | |
| SCHEMBL572949 | 0.79 | TDP1 (0.56) | GAACYP1A2CYP2C9CYP2C19HTT | |
| SCHEMBL27966342 | 0.78 | SYK (0.48) | POLBHTTKMT2AMEN1ALDH1A1 | |
| SCHEMBL23461797 | 0.78 | TDP1 (0.53) | GAAKMT2ACTSKMEN1 | |
| SCHEMBL25095054 | 0.77 | TDP1 (0.58) | GAACYP1A2CYP2C9CYP2C19HTT | |
| SCHEMBL20288786 | 0.77 | CA1 (0.43) | GAAKMT2ACTSKMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007131528-A1 | PROCESS FOR PREPARING C5 INTERMEDIATES AND THEIR USE IN THE PREPARATION OF N-SUBSTITUTED PYRROLE DERIVATIVES | RATIOPHARM GMBH (DE) | 2007-11-22 | — | — | WO | disclosed |