Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | CA1 | P00915 | 4/20 | 0.48 |
| ▸ | CA2 | P00918 | 4/20 | 0.48 |
| ▸ | CA12 | O43570 | 2/20 | 0.48 |
| ▸ | CA9 | Q16790 | 2/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.45 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.45 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9555151 | 0.96 | GAA (0.53) | GAATDP1CYP3A4CA1CA2 | |
| SCHEMBL25095054 | 0.94 | TDP1 (0.58) | GAATDP1CYP3A4CA1CA2 | |
| SCHEMBL7158127 | 0.93 | TDP1 (0.61) | GAATDP1CYP3A4CA1CA2 | |
| SCHEMBL29256392 | 0.93 | TDP1 (0.61) | GAATDP1CYP3A4CA1CA2 | |
| SCHEMBL5653695 | 0.93 | TDP1 (0.61) | GAATDP1CYP3A4CA1CA2 | |
| SCHEMBL8032622 | 0.90 | GAA (0.69) | GAATDP1CYP3A4CA1CA2 | |
| SCHEMBL572949 | 0.90 | TDP1 (0.56) | GAATDP1CYP3A4CA1CA2 | |
| SCHEMBL25181313 | 0.88 | GAA (0.51) | GAATDP1CYP3A4CA1CA2 | |
| SCHEMBL20711494 | 0.87 | MAOA (0.56) | GAATDP1CYP3A4CA1CA2 | |
| SCHEMBL7405019 | 0.87 | GAA (0.64) | GAATDP1CYP3A4CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023125792-A1 | MULTI-SUBSTITUTED URACIL DERIVATIVE AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 杭州奥默医药股份有限公司 | 2023-07-06 | — | — | WO | disclosed |