SCHEMBL5355347

SCHEMBL5355347

CC(=O)Oc1ccc(Sc2ccc(OC(C)=O)cc2)cc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 5/20 0.61
MAPT P10636 4/20 0.55
POLB P06746 1/20 0.55
PKM P14618 1/20 0.55
ELANE P08246 2/20 0.53
HPGD P15428 2/20 0.52
L3MBTL1 Q9Y468 1/20 0.52
HSD17B10 Q99714 2/20 0.52
ALDH1A1 P00352 2/20 0.50
HSP90AA1 P07900 1/20 0.50
GAA P10253 1/20 0.50
MEN1 O00255 3/20 0.48
KMT2A Q03164 3/20 0.48
KDM4E B2RXH2 2/20 0.48
CYP3A4 P08684 2/20 0.48
TTR P02766 1/20 0.48
TP53 P04637 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.48
GLA P06280 1/20 0.47
RAB9A P51151 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3422384 0.92 ELANE (0.61) LMNAMAPTPOLBPKMELANE
SCHEMBL13047614 0.92 LMNA (0.77) LMNAMAPTPOLBPKMELANE
SCHEMBL12023642 0.92 LMNA (0.53) LMNAMAPTPOLBPKMELANE
SCHEMBL9888861 0.90 LMNA (0.52) LMNAMAPTPOLBPKMELANE
SCHEMBL2707663 0.89 HSD17B10 (0.71) LMNAMAPTPOLBPKMELANE
SCHEMBL13133210 0.87 KMT2A (0.54) LMNAMAPTPOLBPKMELANE
SCHEMBL942837 0.86 LMNA (0.61) LMNAMAPTPOLBPKMELANE
SCHEMBL6552544 0.86 MAOA (0.50) LMNAMAPTPOLBPKMELANE
SCHEMBL1088897 0.86 MAPT (0.50) LMNAMAPTPOLBPKMELANE
SCHEMBL269329 0.85 LMNA (0.80) LMNAMAPTPOLBPKMELANE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116874464-A Polymerizable single-component photoinitiator and preparation method thereof 江苏集萃光敏电子材料研究所有限公司 2023-10-13 CN claimed
EP-0252415-B1 Novel polyester polymers IDEMITSU KOSAN CO (JP) 1994-06-08 EP claimed
US-4749775-A PET, ACYLOXY-AROMATIC CARBOXYLIC ACID, DIESTERS, DIIMIDE-DICARBOXYLIC REACTANTS IDEMITSU KOSAN CO., LTD. (JP) 1988-06-07 US claimed
EP-0252415-A2 Novel polyester polymers IDEMITSU KOSAN COMPANY LIMITED (JP) 1988-01-13 EP claimed
CN-116874464-A Polymerizable single-component photoinitiator and preparation method thereof 江苏集萃光敏电子材料研究所有限公司 2023-10-13 CN disclosed
WO-2007129169-A2 COX- II INHIBITORS FOR IMPROVING REPRODUCTIVE SUCCESS IN A FEMALE ANIMAL PFIZER LIMITED (GB) 2007-11-15 WO disclosed
EP-1191929-A4 (Z)-STYRYL ACETOXYPHENYL SULFIDES AS CYCLOOXYGENASE INHIBITORS UNIV TEMPLE (US) 2005-02-16 EP disclosed
US-6656968-B1 Selectively inhibit the cyclooxygenase activity of COX-2 over COX-1; addition polymers of compound TEMPLE UNIVERSITY - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION 2003-12-02 US disclosed
US-6656968-B1 Selectively inhibit the cyclooxygenase activity of COX-2 over COX-1; addition polymers of compound TEMPLE UNIVERSITY - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION 2003-12-02 US disclosed
EP-1191929-A2 (Z)-STYRYL ACETOXYPHENYL SULFIDES AS CYCLOOXYGENASE INHIBITORS Temple University of the Commonwealth System of Higher Education (US) 2002-04-03 EP disclosed
WO-2000077169-A2 (Z)-STYRYL ACETOXYPHENYL SULFIDES AS CYCLOOXYGENASE INHIBITORS TEMPLE UNIVERSITY - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) 2000-12-21 WO disclosed
EP-0252415-B1 Novel polyester polymers IDEMITSU KOSAN CO (JP) 1994-06-08 EP disclosed
EP-0321691-B1 PROCESS FOR PRODUCING AROMATIC POLYESTER IDEMITSU PETROCHEMICAL CO. LTD. (JP) 1993-09-29 EP disclosed
US-4892912-A DEPOLYMERIZATION THEN POLYMERIZING FRAGMENTS, ELASTICITY, MECHANICAL STRENGTH IDEMITSU PETROCHEMICAL CO., LTD. (JP) 1990-01-09 US disclosed
EP-0321691-A2 Process for producing aromatic polyester IDEMITSU PETROCHEMICAL CO. LTD. (JP) 1989-06-28 EP disclosed
US-4749775-A PET, ACYLOXY-AROMATIC CARBOXYLIC ACID, DIESTERS, DIIMIDE-DICARBOXYLIC REACTANTS IDEMITSU KOSAN CO., LTD. (JP) 1988-06-07 US disclosed
EP-0252415-A2 Novel polyester polymers IDEMITSU KOSAN COMPANY LIMITED (JP) 1988-01-13 EP disclosed
US-4542203-A Method for producing branched aromatic polyesters SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1985-09-17 US disclosed
US-4115357-A MOLDING RESINS, FIBERS, COATINGS MONSANTO COMPANY (US) 1978-09-19 US disclosed