Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 4/20 | 0.50 |
| ▸ | MAOB | P27338 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | MGLL | Q99685 | 2/20 | 0.46 |
| ▸ | CUL4A | Q13619 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 2/20 | 0.43 |
| ▸ | F2 | P00734 | 1/20 | 0.43 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.42 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.42 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.42 |
| ▸ | ELANE | P08246 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | IL18 | Q14116 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL337646 | 0.89 | LMNA (0.57) | MAPTALDH1A1LMNAPOLBMGLL | |
| SCHEMBL5355347 | 0.86 | LMNA (0.61) | MAPTALDH1A1LMNAPOLBPKM | |
| SCHEMBL6552705 | 0.85 | MAOA (0.42) | MAOAMAOBMAPTALDH1A1LMNA | |
| SCHEMBL5945230 | 0.84 | HSD17B10 (0.58) | MAPTALDH1A1LMNAPOLBMGLL | |
| SCHEMBL28632338 | 0.83 | MAOA (0.50) | MAOAMAOBMAPTALDH1A1LMNA | |
| SCHEMBL10500433 | 0.83 | MAPT (0.49) | MAPTALDH1A1LMNAMGLLCUL4A | |
| SCHEMBL11125066 | 0.80 | MAPT (0.55) | MAPTALDH1A1LMNAPOLBMGLL | |
| SCHEMBL6323128 | 0.80 | ELANE (0.49) | MAPTALDH1A1LMNAPOLBMGLL | |
| SCHEMBL12023642 | 0.79 | LMNA (0.53) | MAPTALDH1A1LMNAPOLBPKM | |
| SCHEMBL13047614 | 0.79 | LMNA (0.77) | MAOBMAPTALDH1A1LMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1389185-A2 | AMINOALCOHOL DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-02-18 | — | — | EP | disclosed |
| WO-2002094770-A2 | AMINOALCOHOL DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-11-28 | — | — | WO | disclosed |