⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1274033 | 0.89 | — | — | |
| SCHEMBL8465842 | 0.81 | — | — | |
| SCHEMBL5838348 | 0.78 | — | — | |
| SCHEMBL1398246 | 0.78 | — | — | |
| SCHEMBL3679800 | 0.76 | TSHR (0.45) | — | |
| SCHEMBL5486101 | 0.76 | — | — | |
| SCHEMBL9302378 | 0.75 | TSHR (0.37) | — | |
| SCHEMBL332526 | 0.75 | PRKCA (0.32) | — | |
| SCHEMBL14695995 | 0.75 | — | — | |
| SCHEMBL5485747 | 0.74 | TSHR (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2788405-A2 | MONOMER SYSTEMS WITH DISPERSED SILICONE-BASED ENGINEERED PARTICLES | Johnson & Johnson Vision Care Inc. (US) | 2014-10-15 | — | — | EP | claimed |
| US-20130323295-A1 | MONOMER SYSTEMS WITH DISPERSED SILICONE-BASED ENGINEERED PARTICLES | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2013-12-05 | — | — | US | claimed |
| WO-2013085814-A2 | MONOMER SYSTEMS WITH DISPERSED SILICONE-BASED ENGINEERED PARTICLES | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2013-06-13 | — | — | WO | claimed |
| US-9062180-B2 | Polymeric articles comprising oxygen permeability enhancing particles | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2015-06-23 | — | — | US | disclosed |
| EP-2788405-A2 | MONOMER SYSTEMS WITH DISPERSED SILICONE-BASED ENGINEERED PARTICLES | Johnson & Johnson Vision Care Inc. (US) | 2014-10-15 | — | — | EP | disclosed |
| US-20140171541-A1 | POLYMERIC ARTICLES COMPRISING OXYGEN PERMEABILITY ENHANCING PARTICLES | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2014-06-19 | — | — | US | disclosed |
| US-20130323295-A1 | MONOMER SYSTEMS WITH DISPERSED SILICONE-BASED ENGINEERED PARTICLES | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2013-12-05 | — | — | US | disclosed |
| US-8513324-B2 | Polymeric articles comprising oxygen permeability enhancing particles | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2013-08-20 | — | — | US | disclosed |
| WO-2013085814-A2 | MONOMER SYSTEMS WITH DISPERSED SILICONE-BASED ENGINEERED PARTICLES | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2013-06-13 | — | — | WO | disclosed |
| US-20130131214-A1 | POLYMERIC ARTICLES COMPRISING OXYGEN PERMEABILITY ENHANCING PARTICLES | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2013-05-23 | — | — | US | disclosed |
| EP-2414443-A1 | POLYMERIC ARTICLES COMPRISING OXYGEN PERMEABILITY ENHANCING PARTICLES | Johnson & Johnson Vision Care, Inc. (US) | 2012-02-08 | — | — | EP | disclosed |
| WO-2010117588-A1 | POLYMERIC ARTICLES COMPRISING OXYGEN PERMEABILITY ENHANCING PARTICLES | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2010-10-14 | — | — | WO | disclosed |
| US-20100249273-A1 | POLYMERIC ARTICLES COMPRISING OXYGEN PERMEABILITY ENHANCING PARTICLES | JOHNSON & JOHNSON VISION CARE, INC. | 2010-09-30 | — | — | US | disclosed |