Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | ACHE | P22303 | 7/20 | 0.44 |
| ▸ | BCHE | P06276 | 3/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trimethylammonium SCHEMBL11599930 | 0.82 | NCEH1 (0.66) | NCEH1MAPTCYP1A2GAARECQL | |
| SCHEMBL6242893 | 0.81 | LMNA (0.49) | NCEH1MAPTCYP1A2GAARECQL | |
| SCHEMBL27389053 | 0.80 | L3MBTL1 (0.53) | MAPTLMNAALDH1A1KDM4EKMT2A | |
| SCHEMBL27889564 | 0.79 | ALDH1A1 (0.45) | NCEH1MAPTCYP1A2GAARECQL | |
| SCHEMBL28692632 | 0.79 | CYP1A2 (0.43) | NCEH1MAPTCYP1A2GAARECQL | |
| SCHEMBL6024449 | 0.77 | CYP1A2 (0.53) | MAPTCYP1A2GAARECQLLMNA | |
| SCHEMBL2138465 | 0.76 | LMNA (0.70) | NCEH1MAPTCYP1A2GAARECQL | |
| SCHEMBL27574881 | 0.75 | HCAR2 (0.51) | CYP1A2RECQLKMT2ACYP2C19CYP3A4 | |
| SCHEMBL498839 | 0.74 | LMNA (0.63) | MAPTCYP1A2GAARECQLLMNA | |
| SCHEMBL8579809 | 0.74 | KMT2A (0.59) | MAPTCYP1A2GAARECQLLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101296897-A | PPAR-modulating biaromatic compounds | GALDERMA RES & DEV (FR) | 2008-10-29 | — | — | CN | disclosed |
| CN-101022810-A | Novel biaromatic compounds which activate peroxisome proliferator activated receptor-like receptors and their use in cosmetic or pharmaceutical compositions | GALDERMA RES & DEV (FR) | 2007-08-22 | — | — | CN | disclosed |
| CN-1950335-A | Novel biaromatic compounds which activate PPAR.gamma.-type receptors, their process of preparation and their use in cosmetic or pharmaceutical compositions | GALDERMA RES & DEV (FR) | 2007-04-18 | — | — | CN | disclosed |
| US-7164018-B2 | Polymers based on N-carbamyl-N'-dimethylsilyl methyl-piperazine traceless linkers for the solid phase synthesis of phenyl based libraries | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2007-01-16 | — | — | US | disclosed |
| US-20040186243-A1 | Polymers based on N-carbamyl-N'-dimethylsilyl methyl-piperazine traceless linkers for the solid phase synthesis of phenyl based libraries | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2004-09-23 | — | — | US | disclosed |
| US-6740712-B2 | SILICON LINKERS BASED ON CARBAMYL PIPERAZINE MOIETY; USE IN SOLID PHASE SYNTHESIS OF COMPOUNDS OR LIBRARIES OF COMPOUNDS EMBRACING A PHENYL RING IN THEIR STRUCTURE | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2004-05-25 | — | — | US | disclosed |
| EP-1360211-A2 | NEW POLYMERS BASED ON N-CARBAMYL-N'-DIMETHYLSILYL METHYL-PIPERAZINE TRACELESS LINKERS FOR THE SOLID PHASE SYNTHESIS OF PHENYL BASED LIBRARIES | Boehringer Ingelheim Pharma GmbH & Co.KG (DE) | 2003-11-12 | — | — | EP | disclosed |
| US-20020120072-A1 | Polymers based on N-carbamyl-N'-dimethysilyl methyl-piperazine traceless linkers for the solid phase synthesis of phenyl based libraries | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2002-08-29 | — | — | US | disclosed |
| WO-2002060960-A2 | NEW POLYMERS BASED ON N-CARBAMYL-N'-DIMETHYLSILYL METHYL-PIPERAZINE TRACELESS LINKERS FOR THE SOLID PHASE SYNTHESIS OF PHENYL BASED LIBRARIES | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2002-08-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020120072-A1 | Polymers based on N-carbamyl-N'-dimethysilyl methyl-piperazine traceless linkers for the solid phase synthesis of phenyl based libraries | DOT1L, DNMT3L, SMYD2 | NCEH1 4544/4885MAPT 856/4885CYP1A2 2981/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.