Acrylic Acid

Acrylic Acid

SCHEMBL5355846

C=CC(=O)O.C=COc1ccccc1

nearest known ligand 0.46

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.46
AKT1 P31749 1/20 0.45
TGM2 P21980 2/20 0.44
LMNA P02545 1/20 0.43
SMN1; SMN2 Q16637 4/20 0.41
KDM4E B2RXH2 4/20 0.41
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
ALOX15 P16050 2/20 0.41
ALDH1A1 P00352 2/20 0.41
TDP1 Q9NUW8 2/20 0.41
EGFR P00533 1/20 0.41
TP53 P04637 1/20 0.41
CYP3A4 P08684 1/20 0.41
MAPT P10636 1/20 0.41
PKM P14618 1/20 0.41
HPGD P15428 1/20 0.41
ALOX12 P18054 1/20 0.41
JAK1 P23458 1/20 0.41
MAPK1 P28482 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acrylic Acid SCHEMBL28501116 0.94 THRB (0.42) THRBAKT1TGM2LMNASMN1; SMN2
Maleic Acid SCHEMBL9172073 0.89 ALDH1A1 (0.46) THRBAKT1TGM2LMNASMN1; SMN2
Benzene SCHEMBL28860269 0.86 LTA4H (0.45) THRBAKT1TGM2LMNAKMT2A
SCHEMBL35471 0.86
Formic Acid Phenyl Ester SCHEMBL28282093 0.85 THRB (0.44) THRBAKT1TGM2LMNASMN1; SMN2
Acrylic Acid SCHEMBL27653442 0.84 AKT1 (0.50) THRBAKT1TGM2LMNASMN1; SMN2
SCHEMBL28675765 0.84 LTA4H (0.43) THRBAKT1TGM2LMNAKMT2A
Water SCHEMBL28321219 0.84 LTA4H (0.43) THRBAKT1TGM2LMNAKMT2A
Water SCHEMBL27492848 0.84 LTA4H (0.43) THRBAKT1TGM2LMNAKMT2A
Methane SCHEMBL272168 0.84 LTA4H (0.43) THRBAKT1TGM2LMNAKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7217743-B2 Curable white ink KONICA CORPORATION (JP) 2007-05-15 US disclosed
US-20040019128-A1 Curable white ink KONICA CORPORATION (JP) 2004-01-29 US disclosed
US-6480345-B2 Image magnifying/reducing optical device and manufacturing method thereof RICOH COMPANY, LTD. (JP) 2002-11-12 US disclosed
US-20020021501-A1 Image magnifying/reducing optical device and manufacturing method thereof RICOH COMPANY, LTD. (JP) 2002-02-21 US disclosed