Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | CTSS | P25774 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.36 |
| ▸ | HBB | P68871 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6904972 | 0.80 | ALDH1A1 (0.42) | ALDH1A1CHRM2LMNAALOX15CHRM1 | |
| SCHEMBL27451413 | 0.77 | ALDH1A1 (0.40) | ALDH1A1CHRM2LMNAALOX15CHRM1 | |
| SCHEMBL2068454 | 0.77 | ALDH1A1 (0.54) | ALDH1A1CHRM2LMNAALOX15CHRM1 | |
| SCHEMBL7508041 | 0.75 | AR (0.43) | ALDH1A1ARLMNAALOX15L3MBTL1 | |
| Methyl Alcohol SCHEMBL28171303 | 0.73 | ALDH1A1 (0.50) | ALDH1A1CHRM2LMNAALOX15CHRM1 | |
| Potassium Ion SCHEMBL28222970 | 0.73 | ALDH1A1 (0.50) | ALDH1A1CHRM2LMNAALOX15CHRM1 | |
| SCHEMBL796952 | 0.72 | ALDH1A1 (0.45) | ALDH1A1CHRM2LMNAALOX15CHRM1 | |
| SCHEMBL10879176 | 0.72 | ALDH1A1 (0.45) | ALDH1A1CHRM2LMNAALOX15CHRM1 | |
| SCHEMBL16958481 | 0.71 | ALDH1A1 (0.41) | ALDH1A1CHRM2LMNAALOX15CHRM1 | |
| SCHEMBL4649144 | 0.70 | L3MBTL1 (0.37) | ALDH1A1CHRM2LMNAALOX15CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1861356-A1 | IMINES AS ION CHANNEL MODULATORS | Icagen, Inc. (US) | 2007-12-05 | — | — | EP | disclosed |
| WO-2006084031-A1 | IMINES AS ION CHANNEL MODULATORS | ICAGEN, INC. (US) | 2006-08-10 | — | — | WO | disclosed |