Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 6/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.38 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27451413 | 0.85 | ALDH1A1 (0.40) | ALDH1A1CHRM2LMNACHRM1ALOX15 | |
| SCHEMBL4649144 | 0.84 | L3MBTL1 (0.37) | ALDH1A1CHRM2LMNACHRM1ALOX15 | |
| SCHEMBL31195673 | 0.82 | ALDH1A1 (0.39) | ALDH1A1TSHRL3MBTL1MAPTTDP1 | |
| SCHEMBL2068454 | 0.81 | ALDH1A1 (0.54) | ALDH1A1CHRM2LMNACHRM1ALOX15 | |
| SCHEMBL5356008 | 0.80 | ALDH1A1 (0.39) | ALDH1A1CHRM2LMNACHRM1ALOX15 | |
| SCHEMBL5925618 | 0.79 | TSHR (0.41) | ALDH1A1LMNATSHRMAPTGLA | |
| SCHEMBL4454748 | 0.79 | CA2 (0.42) | ALDH1A1ALOX15L3MBTL1MAPTGLA | |
| SCHEMBL9064851 | 0.78 | ATM (0.40) | LMNATSHRL3MBTL1MAPTGLA | |
| SCHEMBL7711448 | 0.78 | ALDH1A1 (0.37) | ALDH1A1CHRM2LMNACHRM1ALOX15 | |
| SCHEMBL9064604 | 0.77 | THRB (0.44) | ALDH1A1L3MBTL1MAPTNPSR1GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6833425-B1 | Filler for plastic formulations based on polyurethane | 3M ESPE AG (DE) | 2004-12-21 | — | — | US | disclosed |