Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 2/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | CMA1 | P23946 | 1/20 | 0.37 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.37 |
| ▸ | ANPEP | P15144 | 1/20 | 0.36 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.36 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.36 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | MITF | O75030 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5354153 | 0.93 | PTGER4 (0.60) | PTGER4CYP2C9HIF1AMEN1KMT2A | |
| SCHEMBL5353892 | 0.92 | PTGER4 (0.59) | PTGER4CYP2C9HIF1AMEN1KMT2A | |
| SCHEMBL2975750 | 0.90 | PTGER4 (0.57) | PTGER4CYP2C9HIF1AMEN1KMT2A | |
| SCHEMBL6702424 | 0.88 | PTGER4 (0.63) | PTGER4CYP2C9HIF1AMEN1KMT2A | |
| SCHEMBL5353199 | 0.88 | PTGER4 (0.77) | PTGER4CYP2C9HIF1AMEN1KMT2A | |
| SCHEMBL6700526 | 0.87 | PTGER4 (0.64) | PTGER4CYP2C9HIF1AMEN1KMT2A | |
| SCHEMBL2981099 | 0.87 | PTGER4 (0.61) | PTGER4CYP2C9HIF1AMEN1KMT2A | |
| SCHEMBL2981280 | 0.86 | PTGER4 (0.57) | PTGER4MEN1KMT2A | |
| SCHEMBL2982780 | 0.86 | PTGER4 (0.58) | PTGER4CYP2C9HIF1AMEN1KMT2A | |
| SCHEMBL2986535 | 0.86 | PTGER4 (0.60) | PTGER4CYP2C9HIF1AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040127487-A1 | Benzoic acid derivatives, processes for the preparation thereof and pharmaceutical agents comprising the same as active ingredient | ONO PHARMACEUTICAL CO., LTD. | 2004-07-01 | — | — | US | claimed |
| US-6710205-B2 | ANTIALLERGENS; ANTICANCER AGENTS; AUTOIMMUNE DISEASES; BONE DISORDERS; RHEUMATIC DISEASES; ANTIULCER AGENTS; SKIN DISORDERS | ONO PHARMACEUTICAL CO., LTD. (JP) | 2004-03-23 | — | — | US | claimed |
| US-20040002493-A1 | Benzoic acid derivatives and pharmaceutical agents comprising the same as active ingredient | ONO PHARMACEUTICAL CO., LTD. (JP) | 2004-01-01 | — | — | US | claimed |
| US-20030114435-A1 | Benzoic acid derivatives, processes for producing the same and drugs containing the same as the active ingredient | ONO PHARMACEUTICAL CO., LTD. (JP) | 2003-06-19 | — | — | US | claimed |
| EP-1314719-A1 | BENZOIC ACID DERIVATIVES AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO., LTD. (JP) | 2003-05-28 | — | — | EP | claimed |
| EP-1258473-A1 | BENZOIC ACID DERIVATIVES, PROCESS FOR PRODUCING THE SAME AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO., LTD. (JP) | 2002-11-20 | — | — | EP | claimed |
| US-7196198-B2 | Benzoic acid derivatives, processes for the preparation thereof and pharmaceutical agents comprising the same as active ingredient | ONO PHARMACEUTICAL CO., LTD. (JP) | 2007-03-27 | — | — | US | disclosed |
| US-7196198-B2 | Benzoic acid derivatives, processes for the preparation thereof and pharmaceutical agents comprising the same as active ingredient | ONO PHARMACEUTICAL CO., LTD. (JP) | 2007-03-27 | — | — | US | disclosed |
| US-7196198-B2 | Benzoic acid derivatives, processes for the preparation thereof and pharmaceutical agents comprising the same as active ingredient | ONO PHARMACEUTICAL CO., LTD. (JP) | 2007-03-27 | — | — | US | disclosed |
| US-20040127487-A1 | Benzoic acid derivatives, processes for the preparation thereof and pharmaceutical agents comprising the same as active ingredient | ONO PHARMACEUTICAL CO., LTD. | 2004-07-01 | — | — | US | disclosed |
| US-6710205-B2 | ANTIALLERGENS; ANTICANCER AGENTS; AUTOIMMUNE DISEASES; BONE DISORDERS; RHEUMATIC DISEASES; ANTIULCER AGENTS; SKIN DISORDERS | ONO PHARMACEUTICAL CO., LTD. (JP) | 2004-03-23 | — | — | US | disclosed |
| US-20040002493-A1 | Benzoic acid derivatives and pharmaceutical agents comprising the same as active ingredient | ONO PHARMACEUTICAL CO., LTD. (JP) | 2004-01-01 | — | — | US | disclosed |
| US-20030114435-A1 | Benzoic acid derivatives, processes for producing the same and drugs containing the same as the active ingredient | ONO PHARMACEUTICAL CO., LTD. (JP) | 2003-06-19 | — | — | US | disclosed |
| EP-1314719-A1 | BENZOIC ACID DERIVATIVES AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO., LTD. (JP) | 2003-05-28 | — | — | EP | disclosed |
| EP-1258473-A1 | BENZOIC ACID DERIVATIVES, PROCESS FOR PRODUCING THE SAME AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO., LTD. (JP) | 2002-11-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040002493-A1 | Benzoic acid derivatives and pharmaceutical agents comprising the same as active ingredient | PTGER1, PTGER4, PTGES | PTGER4 2/4885CYP2C9 187/4885HIF1A 630/4885 |
| US-20030114435-A1 | Benzoic acid derivatives, processes for producing the same and drugs containing the same as the active ingredient | ALOX5, PDGFRB, ALOX15B | PTGER4 71/4885CYP2C9 654/4885HIF1A 422/4885 |
| US-20040127487-A1 | Benzoic acid derivatives, processes for the preparation thereof and pharmaceutical agents comprising the same as active ingredient | PDGFRB, ALOX5, ALOX15B | PTGER4 114/4885CYP2C9 671/4885HIF1A 345/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.