Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNK3 | O14649 | 1/20 | 0.61 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.60 |
| ▸ | RAB9A | P51151 | 3/20 | 0.59 |
| ▸ | BLM | P54132 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | GFER | P55789 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | SENP5 | Q96HI0 | 1/20 | 0.54 |
| ▸ | SENP2 | Q9HC62 | 1/20 | 0.54 |
| ▸ | SENP1 | Q9P0U3 | 1/20 | 0.54 |
| ▸ | F2R | P25116 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3647264 | 0.88 | ALDH1A1 (0.68) | KCNK3KCNK9ALDH1A1RAB9ABLM | |
| SCHEMBL18906015 | 0.84 | ALDH1A1 (0.79) | ALDH1A1HPGDRAB9ABLMMAPT | |
| SCHEMBL5123738 | 0.81 | ALDH1A1 (0.77) | ALDH1A1HPGDRAB9AMAPTSMN1; SMN2 | |
| SCHEMBL27981533 | 0.80 | KCNK3 (0.71) | KCNK3KCNK9ALDH1A1RAB9ABLM | |
| SCHEMBL7165404 | 0.80 | MAPK1 (0.60) | KCNK3KCNK9ALDH1A1RAB9AMAPT | |
| SCHEMBL2747411 | 0.79 | DDX3X (0.65) | HPGDRAB9AMAPTSMN1; SMN2KMT2A | |
| SCHEMBL18906018 | 0.79 | ALDH1A1 (0.69) | ALDH1A1HPGDRAB9ABLMMAPT | |
| SCHEMBL23011774 | 0.78 | ALDH1A1 (0.84) | KCNK3KCNK9ALDH1A1RAB9ABLM | |
| SCHEMBL27952574 | 0.77 | RAB9A (0.65) | KCNK3KCNK9ALDH1A1RAB9AMAPT | |
| SCHEMBL16266238 | 0.77 | ALDH1A1 (1.00) | ALDH1A1HPGDRAB9ABLMMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007136640-A2 | PROCESSES FOR THE PREPARATION OF SUBSTITUTED 2-(2,6-DIOXOPIPERIDIN-3-YL)ISOINDOLE-1,3-DIONE | CELGENE CORPORATION (US) | 2007-11-29 | — | — | WO | disclosed |