Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NT5E | P21589 | 1/20 | 0.70 |
| ▸ | HPGD | P15428 | 1/20 | 0.69 |
| ▸ | TGM2 | P21980 | 1/20 | 0.65 |
| ▸ | HINT1 | P49773 | 4/20 | 0.62 |
| ▸ | PNP | P00491 | 1/20 | 0.60 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.60 |
| ▸ | KRAS | P01116 | 4/20 | 0.59 |
| ▸ | GSK3A | P49840 | 2/20 | 0.59 |
| ▸ | RPS6KA3 | P51812 | 2/20 | 0.59 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.59 |
| ▸ | FUT5 | Q11128 | 1/20 | 0.58 |
| ▸ | IMPDH2 | P12268 | 2/20 | 0.57 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Guanosine SCHEMBL2589323 | 0.97 | NT5E (0.72) | NT5EHPGDTGM2HINT1PNP | |
| Guanosine SCHEMBL1304255 | 0.97 | NT5E (0.72) | NT5EHPGDTGM2HINT1PNP | |
| Guanosine SCHEMBL376138 | 0.97 | NT5E (0.72) | NT5EHPGDTGM2HINT1PNP | |
| Guanosine SCHEMBL44407 | 0.97 | NT5E (0.72) | NT5EHPGDTGM2HINT1PNP | |
| Guanosine SCHEMBL94793 | 0.97 | NT5E (0.72) | NT5EHPGDTGM2HINT1PNP | |
| Guanosine SCHEMBL31361372 | 0.97 | NT5E (0.72) | NT5EHPGDTGM2HINT1PNP | |
| Guanosine SCHEMBL8719176 | 0.96 | NT5E (0.70) | NT5EHPGDTGM2HINT1PNP | |
| Guanosine SCHEMBL9238739 | 0.95 | NT5E (0.69) | NT5EHPGDTGM2HINT1PNP | |
| Guanosine SCHEMBL1444901 | 0.95 | NT5E (0.69) | NT5EHPGDTGM2HINT1PNP | |
| Guanosine SCHEMBL21315718 | 0.95 | HPGD (0.71) | NT5EHPGDTGM2HINT1PNP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7217523-B2 | Nucleoside phosphoramidates and nucleoside phosphoramidases | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2007-05-15 | — | — | US | disclosed |
| US-20060014193-A1 | Nucleoside phosphoramidates and nucleoside phosphoramidases | REGENTS OF THE UNIVERSITY OF MINNESOTA | 2006-01-19 | — | — | US | disclosed |