Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 12/20 | 0.57 |
| ▸ | CNR2 | P34972 | 6/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | CACNA1G | O43497 | 2/20 | 0.57 |
| ▸ | CACNA2D1 | P54289 | 4/20 | 0.54 |
| ▸ | CACNB1 | Q02641 | 4/20 | 0.54 |
| ▸ | CACNA1B | Q00975 | 3/20 | 0.54 |
| ▸ | CACNA1C | Q13936 | 3/20 | 0.54 |
| ▸ | CACNA1A | O00555 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5324471 | 0.84 | CACNA2D1 (0.61) | CNR1CNR2HTTNPSR1CACNA1G | |
| SCHEMBL5333695 | 0.82 | CACNA2D1 (0.58) | CNR1CNR2HTTNPSR1CACNA1G | |
| SCHEMBL5356602 | 0.80 | CACNA1G (0.54) | CNR1CNR2HTTNPSR1CACNA1G | |
| SCHEMBL5359764 | 0.79 | CACNA1G (0.56) | NPSR1CACNA1GCACNA2D1CACNB1CACNA1B | |
| SCHEMBL5372531 | 0.77 | CACNA1G (0.66) | CACNA1GCACNA2D1CACNB1CACNA1BCACNA1C | |
| SCHEMBL5361400 | 0.76 | CACNA2D1 (0.55) | CACNA1GCACNA2D1CACNB1CACNA1BCACNA1C | |
| SCHEMBL3954671 | 0.72 | CACNA1G (1.00) | CNR1CACNA1GCACNA2D1CACNB1CACNA1B | |
| SCHEMBL5266301 | 0.72 | CACNA2D1 (1.00) | CACNA1GCACNA2D1CACNB1CACNA1BCACNA1C | |
| SCHEMBL5268519 | 0.72 | CACNA2D1 (1.00) | CACNA1GCACNA2D1CACNB1CACNA1BCACNA1C | |
| SCHEMBL4179713 | 0.72 | CACNA2D1 (1.00) | CACNA1GCACNA2D1CACNB1CACNA1BCACNA1C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007142431-A1 | NEW NON-PEPTIDE COMPOUNDS, PROCESS FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | EWHA UNIVERSITY - INDUSTRY COLLABORATION FOUNDATION (KR) | 2007-12-13 | — | — | WO | claimed |
| WO-2007142431-A1 | NEW NON-PEPTIDE COMPOUNDS, PROCESS FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | EWHA UNIVERSITY - INDUSTRY COLLABORATION FOUNDATION (KR) | 2007-12-13 | — | — | WO | disclosed |