Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA2D1 | P54289 | 4/20 | 0.58 |
| ▸ | CACNB1 | Q02641 | 4/20 | 0.58 |
| ▸ | CACNA1B | Q00975 | 3/20 | 0.58 |
| ▸ | CACNA1C | Q13936 | 3/20 | 0.58 |
| ▸ | CACNA1G | O43497 | 3/20 | 0.58 |
| ▸ | CACNA1A | O00555 | 1/20 | 0.57 |
| ▸ | CNR1 | P21554 | 10/20 | 0.55 |
| ▸ | CNR2 | P34972 | 6/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5324471 | 0.97 | CACNA2D1 (0.61) | CACNA2D1CACNB1CACNA1BCACNA1CCACNA1G | |
| SCHEMBL5356597 | 0.82 | CNR1 (0.57) | CACNA2D1CACNB1CACNA1BCACNA1CCACNA1G | |
| SCHEMBL5356025 | 0.81 | CACNA1G (0.56) | CACNA2D1CACNB1CACNA1BCACNA1CCACNA1G | |
| SCHEMBL5362020 | 0.79 | CACNA1G (0.63) | CACNA2D1CACNB1CACNA1BCACNA1CCACNA1G | |
| SCHEMBL5360610 | 0.77 | CACNA2D1 (0.57) | CACNA2D1CACNB1CACNA1BCACNA1CCACNA1G | |
| SCHEMBL5325048 | 0.76 | CACNA1G (0.60) | CACNA2D1CACNB1CACNA1BCACNA1CCACNA1G | |
| SCHEMBL5266301 | 0.75 | CACNA2D1 (1.00) | CACNA2D1CACNB1CACNA1BCACNA1CCACNA1G | |
| SCHEMBL5268519 | 0.75 | CACNA2D1 (1.00) | CACNA2D1CACNB1CACNA1BCACNA1CCACNA1G | |
| SCHEMBL4179713 | 0.75 | CACNA2D1 (1.00) | CACNA2D1CACNB1CACNA1BCACNA1CCACNA1G | |
| SCHEMBL5370723 | 0.74 | CACNA1G (0.65) | CACNA2D1CACNB1CACNA1BCACNA1CCACNA1G |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007142431-A1 | NEW NON-PEPTIDE COMPOUNDS, PROCESS FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | EWHA UNIVERSITY - INDUSTRY COLLABORATION FOUNDATION (KR) | 2007-12-13 | — | — | WO | claimed |
| WO-2007142431-A1 | NEW NON-PEPTIDE COMPOUNDS, PROCESS FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | EWHA UNIVERSITY - INDUSTRY COLLABORATION FOUNDATION (KR) | 2007-12-13 | — | — | WO | disclosed |