Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLK1 | P53350 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | EP300 | Q09472 | 2/20 | 0.40 |
| ▸ | HPGDS | O60760 | 1/20 | 0.40 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | CDC25B | P30305 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2070927 | 0.71 | IDO1 (0.44) | PLK1IDO1EP300HPGDSKAT8 | |
| SCHEMBL535326 | 0.70 | PLK1 (0.65) | PLK1IDO1EP300HPGDSKAT8 | |
| SCHEMBL11538213 | 0.70 | CA12 (0.43) | CA12CA1CA2CA4CA7 | |
| SCHEMBL25302185 | 0.69 | IDO1 (0.42) | PLK1IDO1EP300HPGDSKAT8 | |
| SCHEMBL11532746 | 0.69 | PARP1 (0.40) | CA12CA1CA2CA7CA9 | |
| 1,2-Dimethoxybenzene SCHEMBL28118612 | 0.69 | CA1 (0.72) | CA12CA1CA2CA4CA7 | |
| SCHEMBL3088335 | 0.68 | IKBKB (0.45) | CA12CA1CA2CA4CA7 | |
| SCHEMBL30742731 | 0.67 | CDC25B (0.53) | PLK1HPGDSCA12CA1CA2 | |
| SCHEMBL10964177 | 0.67 | CDC25B (0.53) | PLK1HPGDSCA12CA1CA2 | |
| SCHEMBL6254788 | 0.67 | FABP4 (0.42) | CA12CA1CA2CA4CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 156 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1352083-B2 | COMPOSITIONS AND METHODS FOR DETECTING TARGET MICROORGANISMS IN A SAMPLE | BIOCONTROL SYSTEMS INC (US) | 2013-12-25 | — | — | EP | claimed |
| EP-2074089-B1 | ORGANIC COMPOUNDS | NOVARTIS AG (CH) | 2013-09-18 | — | — | EP | claimed |
| US-8222248-B2 | Organic compounds | NOVARTIS AG (CH) | 2012-07-17 | — | — | US | claimed |
| EP-1500707-B1 | METHOD OF MEASURING NEPRILYSIN ACTIVITY | TAKEDA PHARMACEUTICAL (JP) | 2010-09-15 | — | — | EP | claimed |
| US-7572574-B2 | Method of measuring neprilysin activity | RIKEN (JP) | 2009-08-11 | — | — | US | claimed |
| EP-2074089-A2 | ORGANIC COMPOUNDS | Novartis AG (CH) | 2009-07-01 | — | — | EP | claimed |
| WO-2008048991-A2 | ORGANIC COMPOUNDS | NOVARTIS AG (CH) | 2008-04-24 | — | — | WO | claimed |
| US-20060008842-A1 | Method of measuring neprilysin activity | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2006-01-12 | — | — | US | claimed |
| EP-1352083-B1 | COMPOSITIONS AND METHODS FOR DETECTING TARGET MICROORGANISMS IN A SAMPLE | BIOCONTROL SYSTEMS INC (US) | 2005-10-26 | — | — | EP | claimed |
| EP-0946746-B1 | METHOD AND MEDIA FOR THE DETECTION OF YEASTS AND/OR MOLDS IN A SAMPLE | BIOCONTROL SYSTEMS INC (US) | 2005-03-02 | — | — | EP | claimed |
| WO-2002018625-A2 | COMPOSITIONS AND METHODS FOR DETECTING TARGET MICROORGANISMS IN A SAMPLE | BIOCONTROL SYSTEMS, INC. (US) | 2002-03-07 | — | — | WO | claimed |
| US-6022698-A | Method and components for the detection of yeasts and/or molds in a sample | IDEXX LABORATORIES, INCORPORATED (US) | 2000-02-08 | — | — | US | claimed |
| US-5962216-A | MARKER OR ANTICARCINOGENIC/ANTIINFLAMMATORY/ANTITUMOR AGENT LINKED BY CLEAVABLE SEQUENCE TO STABILIZER OF BETA-ALANINE OR SUCCINIC ACID; TARGETED DELIVERY TO CELL, CLEAVAGE BY CELL SPECIFIC FACTOR FOR ENTRY INTO CELL OR EXPRESSION OF MARKER | LA REGION WALLONNE (BE) | 1999-10-05 | — | — | US | claimed |
| US-5854011-A | Method and components for the detection of yeasts and/or molds in a sample | IDEXX LABORATORIES INCORPORATED (US) | 1998-12-29 | — | — | US | claimed |
| WO-1996020949-A1 | PEPTIDE AND PEPTIDE ANALOG PROTEASE INHIBITORS | SIBIA NEUROSCIENCES, INC. (US) | 1996-07-11 | — | — | WO | claimed |
| WO-1996020725-A2 | PEPTIDE, PEPTIDE ANALOG AND AMINO ACID ANALOG PROTEASE INHIBITORS | SIBIA NEUROSCIENCES, INC. (US) | 1996-07-11 | — | — | WO | claimed |
| US-5425942-A | Giant protein complex; useful in screening for cancer | OTSUKA PHARAMCEUTICAL CO., LTD. (JP) | 1995-06-20 | — | — | US | claimed |
| EP-0345750-A2 | Polyfunctional protease | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1989-12-13 | — | — | EP | claimed |
| US-4335204-A | Easily split substrates for the quantification of proteases | KABI AB (SE) | 1982-06-15 | — | — | US | claimed |
| US-4279810-A | Easily split substrates for the quantification of proteases | KABI AB (SE) | 1981-07-21 | — | — | US | claimed |